摘要
目的探讨糖皮质激素联合特布他林治疗慢阻肺急性加重期的效果观察。方法所有入选本次研究且作为研究样本的患者,均为我院2017年7月~2018年8月入院治疗的慢阻肺急性加重期患者,严格核对纳入及排除标准,选取70名患者,将70名患者采用电脑随机分组方法,均分为两组,对照组患者以及观察组患者,分别接受特布他林治疗以及糖皮质激素联合特布他林治疗,对比两组患者在不同治疗方式下FEV1、FVC、FEV1/FVC以及临床治疗效果。结果治疗前,两组患者的FEV1、FVC、FEV1/FVC对比,观察组患者与对照组患者差异无统计学意义(P> 0.05);治疗后,两组患者的FEV1、FVC、FEV1/FVC均有所提升,但是观察组患者FEV1、FVC、FEV1/FVC高于对照组患者,观察组患者的治疗总有效率高于对照组患者,两组患者的数据对比差异有统计学意义(P <0.05)。结论糖皮质激素联合特布他林治疗慢阻肺急性加重期患者,能有效地改善患者的肺通气功能,缓解患者的临床症状,促进疾病的好转,其治疗效果显著,该治疗方法值得临床推广。
Objective To explore the observation on curative effects of glucocorticoid combined with terbutaline in treatment of acute exacerbation of chronic obstructive pulmonary disease. Methods Patients with acute exacerbation of chronic obstructive pulmonary disease who were treated in our hospital from July 2017 to August 2018 were selected as research objects and research samples in the study.The inclusion and exclusion criteria were strictly checked and 70 patients were selected.70 patients were randomly divided into the control group and the observation group according to computer random grouping method.Patients in the control group were treated with terbutaline while patients in the observation group were treated with glucocorticoid combined with terbutaline.FEV1,FVC,FEV1/FVC and clinical curative effects were compared between the two groups under different treatment methods. Results Before treatment,FEV1,FVC and FEV1/FVC were compared between patients in the two groups.There was no statistically significant difference between the observation group and the control group(P > 0.05).After treatment,FEV1,FVC and FEV1/FVC in both groups were improved.However,FEV1,FVC and FEV1/FVC in the observation group were higher than those in the control group.The total effective rate of treatment in the observation group was higher than that in the control group.The difference between the two groups was statistically significant(P < 0.05). Conclusion Glucocorticoid combined with terbutaline in treatment of acute exacerbation of chronic obstructive pulmonary disease can effectively improve the pulmonary ventilation function of patients,relieve the clinical symptoms of patients and promote the improvement of the disease.Its curative effect is significant and the method is worthy of clinical promotion.
作者
杨圣艮
YANG Shenggen(Respiratory Department,Luohu District People's Hospital,Shenzhen 518000,China)
出处
《中国医药科学》
2019年第23期64-66,共3页
China Medicine And Pharmacy
关键词
糖皮质激素
特布他林
慢阻肺急性加重期
肺功能
Glucocorticoid
Terbutaline
Acute exacerbation of chronic obstructive pulmonary disease
Lung function
