摘要
目的观察硬通道与软通道配合侧脑室内尿激酶灌注外引流治疗全脑室系统铸型血肿的疗效。方法回顾分析2009年1月~2018年12月在本院接受治疗的全脑室系统铸型血肿患者70例,按照治疗方式的差异分为硬通道组和软通道组,每组35例,两组患者拔管后予腰椎穿刺或腰大池引流。比较两组患者的手术相关指标、并发症发生率以及治疗效果。结果硬通道组手术时间、脑室内血肿廓清时间、引流拔管时间均短于软通道组(P <0.05);硬通道组并发症发生率为11.43%,明显低于软通道组的34.29%(P <0.05);硬通道组治疗有效率为68.57%,显著高于软通道组的37.14%(P <0.05)。结论硬通道侧脑室额角穿刺外引流配合尿激酶10万单位脑室内灌注治疗脑室铸型血肿安全有效,血肿廓清速度快,且降低了并发生发生率,有利于促进患者术后恢复。
Objective To observe the efficacy of hard channel and soft channel combined with lateral cerebral ventricle perfusion and external drainage for the treatment of cast hematoma in the whole ventricle system. Methods Retrospective analysis of 70 patients with whole ventricular system cast hematoma treated in our hospital from January 2009 to December 2018,divided into hard channel group and soft channel group according to the difference of treatment methods,35 cases in each group,two groups of patients Lumbar puncture or lumbar drainage after extubation.Surgical related indicators,complication rates,and treatment effects were compared between the two groups. Results The operation time,intracranial hematoma clearance time and drainage time were shorter in the hard channel group than in the soft channel group(P < 0.05).The complication rate in the hard channel group was 11.43%,which was significantly lower than that in the soft channel group(34.29%)(P < 0.05);The effective rate of the hard channel group was 68.57%,which was significantly higher than that of the soft channel group(37.14%)(P < 0.05). Conclusion The external drainage of the lateral ventricle of the hard ventricle combined with the intraventricular perfusion of 100,000 units of urinary carb were safe and effective.The hematoma clearance is fast and the incidence is reduced,which is beneficial to promote postoperative recovery.
作者
江勇豪
翟柱文
黄国豪
冯清亮
JIANG Yonghao;ZHAI Zhuwen;HUANG Guohao;FENG Qingliang(Department of Neurosurgery,Huangjiang Hospital,Dongguan 523000,China)
出处
《中国医药科学》
2019年第23期244-246,263,共4页
China Medicine And Pharmacy
基金
广东省东莞市社会科技发展一般项目（201750715041466）
关键词
全脑室铸型血肿
硬通道
软通道
尿激酶
外引流
Whole ventricle cast hematoma
Hard channel
Soft channel
Urinary bacterium
External drainage
