摘要
目的探讨盐酸舍曲林联合叙事心理治疗对抑郁症的效果及对患者生活满意度的影响。方法选择2015年7月-2018年6月在珠海市慢性病防治中心住院及门诊治疗的、符合《国际疾病分类(第10版)》(ICD-10)诊断标准的抑郁症患者64例,采用随机数字表法分为研究组和对照组各32例,其中研究组采用盐酸舍曲林联合叙事心理治疗,对照组单纯给予盐酸舍曲林治疗,两组均治疗16周。于治疗前及治疗第2、4、8、12、16周采用汉密顿抑郁量表24项版(HAMD-24)评定疗效,采用生活满意度指数A量表(LSIA)评定患者生活满意度。结果同组内不同治疗时间的HAMD-24总评分比较差异有统计学意义(F=439.462,P<0.01);两组之间HAMD-24总评分的差异有统计学意义(F=7.035,P<0.05);不同治疗时间和治疗方法间存在交互作用(F=4.791,P<0.01)。同组内不同治疗时间的LSIA评分差异有统计学意义(F=260.555,P<0.01);两组之间LSIA评分差异有统计学意义(F=26.750,P<0.01);不同治疗时间和治疗方法间存在交互作用(F=14.841,P<0.01)。两组不良反应发生率差异无统计学意义(χ2=0.231,P>0.05)。结论与单用盐酸舍曲林相比,盐酸舍曲林联合叙事心理治疗可能更有助于改善抑郁症状、提高患者生活满意度。
Objective To explore the efficacy and life satisfaction of sertraline hydrochloride combined with narrative psychotherapy for patients with depression disorder.Methods From July 2015 to June 2018,a total of 64 outpatients and inpatients with depression disorder in Zhuhai Center for Chronic Disease Control who met the diagnostic criteria of International Classification of Diseases,tenth edition(ICD-10)were selected,and were randomly divided into the research group(n=32)and the control group(n=32)by random number table method.The research group was treated with sertraline hydrochloride tablets combined with narrative psychotherapy,while the control group was simply given sertraline hydrochloride tablets.Both groups were treated for 16 weeks.The efficacy was evaluated by the Hamilton Depression Scale-24 item(HAMD-24),and the satisfaction of life was assessed by the Life Satisfaction Index A(LSIA)before treatment and at the 2nd,4th,8th,12th,16th weeks of the treatment.Results The HAMD-24 total scores of different treatment periods showed statistically significant difference within groups(F=439.462,P<0.01).The difference of HAMD-24 total score between the two groups was also statistically significant(F=7.035,P<0.05).There were interactions between different treatment times and treatment methods(F=4.791,P<0.01).The LSIA scores of different treatment periods showed statistically significant difference within groups(F=260.555,P<0.05).The difference of LSIA scores between the two groups was also statistically significant(F=26.750,P<0.05).There were interactions between different treatment times and treatment methods(F=14.841,P<0.05).There was no significant difference in adverse reactions between the two groups(χ2=0.231,P>0.05).Conclusion Compared with sertraline hydrochloride alone,the combination with narrative psychotherapy has more obvious effect in improving the efficacy and life satisfaction of patients with depression disorder.
作者
王雀良
谢志兵
梁美玲
蔡华玲
高瞻
Wang Queliang;Xie Zhibing;Liang Meiling;Cai Hualing;Gao Zhan(Zhuhai Center for Chronic Disease Control,Zhuhai 519000,China)
出处
《四川精神卫生》
2019年第6期506-509,共4页
Sichuan Mental Health
基金
珠海市科技计划项目（2014D0401990025）
关键词
叙事心理治疗
抑郁症
生活满意度
Narrative psychotherapy
Depression
Satisfaction of life
