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SUMF在哮喘发病机制中作用的研究进展 被引量:2

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摘要 支气管哮喘(简称哮喘)是一种以气道炎症、气道高反应性和气道重塑为特征的慢性呼吸系统疾病,近十余年来其发病率呈现持续上升趋势。随着对哮喘发病机制研究的不断深入,发现白细胞介素13(IL-13)在哮喘的发病机制中起到中轴的作用。有研究表明,硫酸酯酶修饰因子(SUMF)不仅可以与IL-13相结合,且可以抑制IL-13的分泌,推测SUMF在哮喘的发病机制中起到重要作用,这可能为哮喘的防治提供新的线索。作者就SUMF在哮喘发病机制中作用的研究进展作一综述。
出处 《东南大学学报(医学版)》 CAS 2019年第6期1103-1106,共4页 Journal of Southeast University(Medical Science Edition)
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