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西咪替丁联合兰索拉唑治疗消化性溃疡出血的疗效及对胃内pH值的影响

Effect of cimetidine combined with lansoprazole in the treatment of peptic ulcer bleeding and its effect on gastric pH
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摘要 目的:探讨采用西咪替丁联合兰索拉唑治疗消化性溃疡出血的临床效果。方法:2017年2月-2019年2月收治消化性溃疡出血患者78例,随机分为两组,各39例。对照组单用西咪替丁治疗,观察组使用西咪替丁联合兰索拉唑治疗,观察两组治疗效果。结果:观察组治疗总有效率明显高于对照组,出血停止时间、疼痛消失时间明显短于对照组,治疗后胃内pH值优于对照组,差异有统计学意义(P<0.05)。结论:采用西咪替丁与兰索拉唑联合治疗消化性溃疡出血,可取得满意的治疗效果。 Objective:To explore the effect of cimetidine combined with lansoprazole in the treatment of peptic ulcer bleeding.Methods:From February 2017 to February 2019,78 patients with peptic ulcer bleeding were selected and randomly divided into two groups of 39 cases in each.The control group was treated with cimetidine,and the observation group was treated with cimetidine combined with lansoprazole.We observed the therapeutic effect of the two groups.Results:In the observation group,the total effective rate of the treatment was significantly higher than that of the control group,and the bleeding stopping time and pain disappearing time were significantly shorter than that of the control group;after treatment,the pH value in the stomach was better than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:The combination of cimetidine and lansoprazole in the treatment of peptic ulcer bleeding can achieve satisfactory results.
作者 陈波 Chen Bo(The Traditional Chinese Medical Hospital of Hongshan District,Wuhan City(Luonan Street Community Health Service Center),Hubei,Wuhan 430070)
出处 《中国社区医师》 2019年第36期74-75,共2页 Chinese Community Doctors
关键词 西咪替丁 兰索拉唑 消化性溃疡出血 Cimetidine Lansoprazole Peptic ulcer bleeding
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