期刊文献+

帕金森病焦虑患者的临床特征研究 被引量:8

Clinical Characteristics of Patients with Parkinson’s Disease Combined with Anxiety
下载PDF
导出
摘要 目的:分析帕金森病(PD)患者焦虑的临床特征和危险因素。方法:横断面调查PD患者,记录患者性别、起病年龄、病程、初始症状、改良H-Y分级、MDS-UPDRS-Ⅲ评分、是否伴发不安腿综合征(RLS)、贝克焦虑量表等临床资料,采用多变量Logistic方法分析PD焦虑的影响因素。结果:共收集263例PD患者,合并焦虑65例(24.7%),其中女性占36例。病程越长、H-Y分级和MDS-UPDRS-Ⅲ评分更高、伴发RLS的患者更易发生焦虑(P<0.05),与起病年龄、文化程度、初始症状等方面无明显相关性(P>0.05)。结论:女性、病程更长、运动功能更严重、合并RLS是PD发生焦虑的危险因素。 Objective: To investigate the clinical characteristics of Parkinson’s disease(PD) with anxiety and explore its risk factors. Methods: A cross-sectional study of PD patients was carried out in the outpatient department of our hospital and Beijing Tiantan Hospital. The clinical characteristics such as age of onset, disease duration, initial symptoms, modified H-Y stages, MDS-UPDRS-Ⅲ, combination with restless legs syndrome(RLS), and Becker anxiety scale scores were collected. The incidence and influencing factors of anxiety in PD were analyzed by multivariate logistic method. Results: A total of 263 PD patients were included;65 patients(24.7%) had anxiety, and 36 of these patients were female. Longer course of disease,higher H-Y stages and MDS-UPDRS-Ⅲ scores, and combination with RLS were positively related with anxiety(P<0.05), but there was no significant correlation between anxiety and the age of onset, education level, or initial symptoms(P>0.05). Conclusion: Being female, longer duration of disease, more severe motor function, and combination with RLS are risk factors for PD with anxiety.
作者 万志荣 王桂华 陈宇 张绿明 冯涛 WAN Zhi-Rong;WANG Gui-Hua;CHEN Yu;ZHANG Lv-ming;FENG Tao(Department of Neurology,Aerospace Central Hospital,Beijing 100049,China;Department of Dyskinetic Disease,Affiliated Beijing Tiantan Hospital of Capital Medical University,Beijng 100070,China)
出处 《神经损伤与功能重建》 2020年第1期14-16,54,共4页 Neural Injury and Functional Reconstruction
关键词 帕金森病 焦虑 贝克焦虑量表 女性 不宁腿综合征 Parkinson’s disease anxiety Beck Anxiety Inventory female restless legs syndrome
  • 相关文献

参考文献7

二级参考文献51

  • 1母艳蕾,陈海波.帕金森病与不宁腿综合征[J].中国现代神经疾病杂志,2007,7(1):18-21. 被引量:1
  • 2Ondo WG,He Y,Rajasekaran S,et al.Clinical correlates of 6-hydroxydopamine injections into A11 dopaminergic neurons in rats:a possible model for restless legs syndrome.Mov Disord,2000,15:154-158.
  • 3Poewe W,H(o)gl B.Akathisia,restless legs and periodic limb movements in sleep in Parkinson's disease.Neurology,2004,63(8 Suppl 3):S12-16.
  • 4Gibb WR,Lees AJ.The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease.J Neurol Neurosurg Psychiatry,1988,51:745-752.
  • 5Allen RP,Picchietti D,Hening WA,et al.Restless legs syndrome:diagnostic criteria,special considerations,and epidemiology.A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health.Sleep Med,2003,4:101-119.
  • 6Buysse DJ,Reynolds CF 3rd,Monk TH,et al.The Pittsburgh Sleep Quality Index:a new instrument for psychiatric practice and research.Psychiatry Res,1989,28:193-213.
  • 7Johns MW.A new method for measuring daytime sleepiness:the Epworth sleepiness scale.Sleep,1991,14:540-545.
  • 8Nomura T,Inoue Y,Miyake M,et al.Prevalence and clinical characteristics of restless legs syndrome in Japanese patients with Parkinson's disease.Mov Disord,2006,21:380-384.
  • 9Ferini-Strambi L,Bonati MT,Oldani A,et al.Genetics in restless legs syndrome.Sleep Med,2004,5:301-304.
  • 10Ondo WG,Vuong KD,Jankovic J.Exploring the relationship between Parkinson disease and restless legs syndrome.Arch Neurol,2002,59:421-424.

共引文献103

同被引文献63

引证文献8

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部