摘要
目的探讨非甲状腺病态综合征(NTIS)合并系统性红斑狼疮(SLE)的临床特点,为临床诊治提供参考。方法便利选取2016年1月—2019年3月该院45例接受甲状腺功能检查的SLE患者为研究对象,依据检查结果分为NTIS组(8例)和正常组(37例),比较观察两组NEWS评分、SLEDAI评分及实验室指标。结果NTIS组NEWS(3.2±0.8)分、肺部改变率37.50%、肾脏改变率62.50%,心脏改变25.00%,24 h尿蛋白定量(1235.7±486.2)mg,肌酐(75.9±18.4)μmol/L,IgG(17.6±5.0)g/L,IgM(1.39±0.61)g/L,C3(0.52±0.27)g/L,与正常组差异有统计学意义(t=3.416,χ^2=6.314,5.631,3.452,t=22.740,4.877,3.847,3.192,3.055)。结论SLE合并NTIS病情程度相对严重,与单纯SLE在临床表现与实验室指标方面存在一定差异,应引起临床重视,加强警惕与防治。
Objective To investigate the clinical characteristics of non-thyroid sick syndrome(NTIS)with systemic lupus erythematosus(SLE)and to provide reference for clinical diagnosis and treatment.Methods Convenient elected 45 SLE patients who underwent thyroid function examination in the hospital from January 2016 to March 2019 were divided into NTIS group(8 cases)and Normal group(37 cases).The NEWS score,SLEDAI score and laboratory indexes were compared between the two groups.Results The NTIS group had NEWS(3.2±0.8)points,lung change rate 37.50%,kidney change rate 62.50%,heart changes were 25.00%,24 h urine protein quantitation(1235.7±486.2)mg,creatinine(75.9±18.4)μmol/L,IgG(17.6±5.0)g/L,IgM(1.39±0.61)g/L,C3(0.52±0.27)g/L,which was statistically different from the Normal group(t=3.416,χ^2=6.314,5.631,3.452,t=22.740,4.877,3.847,3.192,3.055).Conclusion The degree of SLE combined with NTIS is relatively serious,and there is a certain difference between clinical manifestations and laboratory indicators of SLE alone,which should cause clinical attention and strengthen vigilance and prevention.
作者
刘丽蓉
LIU Li-rong(Department of Rheumatology and Immunology,Changshu First People's Hospital,Changshu,Jiangsu Province,215500 China)
出处
《中外医疗》
2019年第34期57-59,共3页
China & Foreign Medical Treatment
关键词
系统性红斑狼疮
非甲状腺病态综合征
临床特点
Systemic lupus erythematosus
Non-thyroid syndrome
Clinical characteristics
