摘要
目的通过实际调查,探究红细胞不规则抗体筛查在临床输血中的作用,并且避免溶血性输血反应的发生。方法首先选取2016年5月—2017年5月该院接收的220例住院申请中需要进行输血的患者,采取微柱凝胶技术进行患者红细胞不规则阳性抗体筛查和鉴定,最后进行交叉配血处理,分析患者红细胞阳性检出情况以及对临床输血的影响。结果通过对比输血之后的各项身体指标,发现在这220例患者当中,有8例患者的检测结果为不规则抗体阳性,阳性检出率为3.6%,进行不规则抗体血型检测之后,发现220患者中有7例患者为RH,MNSs系统为2例,抗A1患1例。通过将8例不规则抗阳性标本进行交叉配血,发现供血者没有产生相应的抗原红细胞,同时大大降低了溶血性输血反应的发生概率。结论通过实际调查分析,在临床输血时进行必要的不规则抗体筛查,可以有效避免患者体内的溶血性输血反应,提高患者的临床输血效果,保证了临床用血的安全,值得临床推广。
Objective To explore the role of irregular red blood cell antibody screening in clinical blood transfusion and to avoid hemolytic transfusion reaction through actual investigation.Methods First of all,we selected 220 patients who needed blood transfusion in the hospital from May 2016 to May 2017.We used microcolumn gel technology to screen and identify the irregular antibodies of red blood cells.Finally,cross matching therapy was used to analyze the positive situation of red blood cells and the influence on clinical transfusion.Results By comparing various physical indicators after blood transfusion,it was found that 8 cases of the 220 patients were positive for irregular antibodies,the positive detection rate was 3.6%.After irregular antibody blood group testing,7 cases of the 220 patients were found to be RH,2 cases were found to be MNSs system and 1 cases was found to be anti-A1.By cross matching 8 cases irregular anti-positive samples,it was found that the donor did not produce corresponding antigen red blood cells,and the probability of hemolytic transfusion reaction was greatly reduced.Conclusion Through actual investigation and analysis,the necessary irregular antibody screening in clinical blood transfusion can effectively avoid the hemolytic transfusion reaction in patients,improve the clinical transfusion effect and ensure the safety of clinical blood transfusion,which is worthy of clinical promotion.
作者
褚庆萍
CHU Qing-ping(People's Hospital of Lingcheng District,Dezhou City,Dezhou,Shandong Province,253500 China)
出处
《中外医疗》
2019年第34期190-192,共3页
China & Foreign Medical Treatment
关键词
红细胞
不规则抗体
溶血性输血反应
Erythrocyte
Irregular antibody
Hemolytic transfusion reaction
