摘要
目的:探讨胺碘酮和西地兰治疗急诊危重症合并快速心律失常疾病的临床应用方法和治疗效果。方法:选择笔者所在医院2018年1月-2019年4月收治的急诊危重症合并快速心律失常患者80例,采用随机数字表法将其分为观察组和对照组,每组40例。所有患者给予支持性抢救措施治疗,对照组在此基础上采用西地兰治疗,观察组在此基础上采用胺碘酮治疗。比较两组患者起效时间、治疗前后LVEF、LVEDD等心功能改善情况、血糖水平、血胰岛素水平及不良反应发生情况。结果:观察组患者起效时间为(17.2±2.9)min,短于对照组的(35.4±5.4)min,差异有统计学意义(P<0.05)。治疗后观察组患者LVEF、LVEDD、E峰值与E/A值等心功能指标高于对照组,A峰值低于对照组,差异均有统计学意义(P<0.05)。治疗前两组血糖水平和血胰岛素水平比较,差异均无统计学意义(P>0.05);治疗后两组血糖水平和血胰岛素水平均有明显改善,且观察组改善情况优于对照组,差异有统计学意义(P<0.05)。观察组患者不良反应发生率为2.5%,低于对照组的15.0%,差异有统计学意义(P<0.05)。结论:与西地兰的药效相比,应用胺碘酮治疗急诊危重症合并快速心律失常患者起效快、疗效好,能够帮助患者更好地改善心功能,稳定血糖水平和血胰岛素水平,安全可靠,具有较高的临床应用价值,值得广泛推广和应用。
Objective:To explore the clinical application and therapeutic effect of Amiodarone and Cedilanid in the treatment of emergency critical illness with tachyarrhythmia.Method:A total of 80 patients with emergency critical illness with tachyarrhythmia admitted in our hospital from January 2018 to April 2019 were selected.They were divided into the observation group and the control group by random number table method,40 cases in each group.All patients were treated with supportive rescue measures.The control group was treated with Cedilanid on this base,and the observation group was treated with Amiodarone on this base.The onset time,improvement of heart function such as LVEF and LVEDD before and after treatment,blood glucose level,and blood insulin levels and occurrence of adverse reactions in the two groups were compared.Result:The onset time of the observation group was(17.2±2.9)min,which was shorter than(35.4±5.4)min of the control group,and the difference was statistically significant(P<0.05).After treatment,the heart function indexes such as LVEF,LVEDD,E peak value and E/A value in the observation group were higher than those in the control group,and the A peak value was lower than that in the control group,the differences were statistically significant(P<0.05).There were no significant differences in blood glucose level and blood insulin level between the two groups before treatment(P>0.05).After treatment,the blood glucose level and insulin level of the two groups were significantly improved,and the improvement of the observation group was better than that of the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 2.5%,which was lower than 15.0%in the control group,and the difference was statistically significant(P<0.05).Conclusion:Compared with the efficacy of Cedilanid,the application of Amiodarone has a fast onset and good effect in the treatment of emergency critical illness with tachyarrhythmia.It can help patients better improve heart function,stabilize blood glucose level and blood insulin levels.It is safe and reliable.It has high clinical application value and is worth popularizing and applying widely.
作者
戴晓金
杨雪平
DAI Xiaojin;YANG Xueping(The First Hospital of Longyan City,Longyan 364000,China)
出处
《中外医学研究》
2019年第35期47-49,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
胺碘酮
西地兰
急诊危重症
快速心律失常
Amiodarone
Cedilanid
Emergency critical illness
Tachyarrhythmia
