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针刀治疗腕管综合征疗效的系统评价和Meta分析 被引量:14

Acupotomy Therapy for Carpal Tunnel Syndrome: a Systematic Review and Meta-Analysis
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摘要 目的:对针刀疗法治疗腕管综合征的有效性和安全性进行评价。方法:计算机检索中国知网(CNKI)、万方数据库(WANFANG DATA)、中国生物医学文献数据库(CBM)、维普数据库(VIP)、PubMed、Cochrane library(2018年第9期)中有关针刀疗法治疗腕管综合征的临床随机对照试验。数据根据Cochrane系统评价手册的要求由两名评价者单独提取,然后交叉核对。数据分析采用RevMan 5.3软件。结果:最后纳入10个临床随机对照试验,共848例腕管综合征患者。Meta分析结果显示针刀组在治疗腕管综合征总有效率[OR=5.61,95%CI(3.53,8.90),P<0.000 01]、治愈率[OR=2.56,95%CI(1.90,3.46),P<0.000 01]、视觉模拟评分(VAS)[MD=-1.43,95%CI(-1.92,-0.95),P<0.000 01]、症状及功能问卷调查表(Levine)[MD=-0.73,95%CI(-1.45,-0.00),P=0.05]方面均优于对照组。结论:针刀治疗腕管压综合征疗效尚可,且优于对照组。但由于纳入实验数有限且文献质量不高,是以需展开大样本高质量随机对照试验来进一步验证。 Objective:To evaluate the clinical efficacy and safety of acupotomytherapy for carpal tunnel syndrome.Methods:Randomized controlled trials(RCTs)of acupotomytherapy for carpal tunnel syndromewere retrieved from CNKI,WANFANG DATA,CBM,VIP,PubMed and Cochrane library(Issue 9,2018).The date was extracted and evaluated by two reviewers independently according to Cochrane Reviewers’Handbook.The Cochrane Collaboration’s RevMan 5.3 software was used for Meta-analysis.Results:Ten RCTs involving 848 cases were included.The results of Meta-analysis showed the acupotomytherapy group was superior to the control group in improving total effect rate[OR=5.61,95%CI(3.53,8.90),P<0.00001],cure rate[OR=2.56,95%CI(1.90,3.46),P<0.00001],visual analogue score(VAS)[MD=-1.43,95%CI(-1.92,-0.95),P<0.00001],symptom and function questionnaire(Levine)[MD=-0.73,95%CI(-1.45,-0.00),P=0.05].Conclusion:Acupotomytherapy is effectivefor treating carpal tunnel syndrome.However,the included studies are of low quality with a small sample size.Based on the deficiency,our conclusion still needs to be comfirmed by more rigorously designed RCTs.
作者 廖安庭 李林 刘福水 游建宇 陈梅 方婷 金玉立 谢金梅 陈辉 LIAO Anting;LI Lin;LIU Fushui;YU Jianyu;CHEN Mei;FANG Ting;JING Yuli;XIE Jinmei;CHEN Hui(School of Acupuncture and Massage,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,Jiangxi,China;The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Nanchang 330006,Jiangxi,China)
出处 《中华中医药学刊》 CAS 北大核心 2019年第12期2941-2947,共7页 Chinese Archives of Traditional Chinese Medicine
基金 国家自然科学基金项目(81560792) 江西省教育厅科学技术研究项目(重点项目)(GJJ170702) 江西省卫生与计划生育委员会科技计划项目(20185514) 江西省卫生与计划生育委员会中医药科研项目(重点课题)(2016Z03)
关键词 腕管综合征 针刀疗法 系统评价 META分析 循证医学 carpal tunnel syndrome acupotomy systematic review Meta-analysis evidence-based medicine
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