摘要
目的:探讨桃红二膝汤在膝骨关节炎患者中的应用效果。方法:收集医院2015年4月—2017年8月间就诊的120例膝骨关节炎患者,随机分为观察组和对照组,各60例。对照组给予双醋瑞因治疗,观察组在此基础上给予桃红二膝汤治疗,共治疗1.5个月。观察两组患者中医症候疗效、骨关节炎指数(WOMAC)、关节液IL-lβ水平及不良反应发生率。结果:治疗1.5个月后,观察组患者中医症候疗效及WOMAC评分均优于对照组(P<0.05),且IL-lβ水平明显低于对照组(P<0.05)。此外观察组患者不良发应的发生率明显低于对照组(P<0.05)。结论:桃红二膝汤治疗膝骨关节炎有较好的临床疗效,且不良反应发生率低。
Objective:The objective of this article is to investigate the clinical effect of application of Taohong Erxi Decoction combined with diacerein on knee osteoarthritis.Methods:A total of 120 patients with with knee osteoarthritis in our hospital from April 2015 to August 2017 were randomly divided into two groups and there were 60 patients in each group.The control group received diacerein and the observation received Taohong Erxi Decoction combined with diacerein.The duration of treatment was one month and a half.The clinical effect of traditional Chinese medicine(TCM)syndrome,scores of the WOMAC,level of IL-lβand side effects rate were compared between observation group and control group.Results:After treatment,the TCM syndrome and scores of the WOMAC in observation group were better than those of the control group(P<0.05).The level of IL-lβwas lower in the observation group(P<0.05).The adverse effects rate in observation was lower than that of the control group(P<0.05).Conclusion:Taohong Erxi Decoction combined with diacerein has a better effect on knee osteoarthritis with lower adverse effects rate.
作者
郑陶
许治国
许志宇
张国江
ZHENG Tao;XU Zhiguo;XU Zhiyu;ZHANG Guojiang(Orthopedics Department,Tangshan Hospital of TCM,Tangshan 063000,Hebei,China)
出处
《中华中医药学刊》
CAS
北大核心
2019年第12期3070-3072,共3页
Chinese Archives of Traditional Chinese Medicine
基金
河北省中医药管理局科研计划项目(2018311)
关键词
桃红二膝汤
膝骨关节炎
临床疗效
Taohong Erxi Decoction
knee osteoarthritis
clinical effect
