摘要
缺血性脑卒中是由于各种脑血管病变所致脑部血液供应障碍,导致局部脑组织缺血、缺氧性坏死,而迅速出现相应神经功能缺损的一类临床综合征。近年来现代医学提出了缺血性脑卒中的神经血管单元机制。针刺以中医的辨证论治、整体观念为原则,具有多靶点、多环节作用的优势,对该病有良好的临床疗效,且已有研究表明,针刺对神经血管单元各主要成分及整体都有显著作用。本文分别从针刺对血脑屏障、星形胶质细胞、小胶质细胞、神经元及神经血管单元整体等5个方面的调控进行综述。
Ischemic stroke is a type of clinical syndrome caused by brain blood supply disorders due to various cerebrovascular diseases,which lead to local cerebral ischemia,hypoxic necrosis,and corresponding neurological defects.In recent years,the neurovascular unit mechanism of ischemic stroke has been proposed in modern medicine.With the principles of syndrome differentiation-based treatment and holistic view in traditional Chinese medicine,acupuncture has the advantage of multi-target and multi-link effect and good clinical efficacy on this disease,and current studies have shown that acupuncture has a marked effect on each component and the whole of neurovascular unit.This article reviews the effect of acupuncture on the regulation of blood-brain barrier,astrocytes,microglial cells,neurons,and neurovascular units.
作者
李广大
韩永升
LI Guang⁃da;HAN Yong⁃sheng(Graduate School of Anhui University of Chinese Medicine,Hefei 230012,China;Affiliated Hospital of Neurology Institute,Anhui University of Chinese Medicine,Hefei 230061)
出处
《针刺研究》
CAS
CSCD
北大核心
2019年第12期863-866,共4页
Acupuncture Research
基金
国家自然科学基金面上项目(No.8177151735)
关键词
缺血性脑卒中
神经血管单元机制
针刺
多靶点
Ischemic stroke
Neurovascular unit mechanism
Acupuncture
Multi-target
