摘要
目的评价血速升颗粒联合蔗糖铁治疗胃癌切除术后合并缺铁性贫血患者的疗效及安全性。方法选取胃癌手术后合并缺铁性贫血的患者98例随机分为联合组和单药组,两组患者术后均给予蔗糖铁治疗,联合组加用血速升颗粒,比较治疗前后贫血指标的变化及药物不良反应情况。结果治疗后,联合组血红蛋白含量、红细胞压积、血清铁蛋白水平等较单药组增高,且差异有统计学意义。联合组治疗贫血总有效率及显效率高于单药组,且差异均有统计学意义。两组治疗后,中医症状记分均较治疗前减小。用药过程中,两组不良反应比较,差异无统计学意义。结论血速升颗粒联合蔗糖铁治疗可改善胃癌手术后合并缺铁性贫血患者的血红蛋白含量、红细胞压积、红细胞平均血红蛋白量、血清铁蛋白水平,并可改善贫血症状,较单用蔗糖铁效果更佳,且联合用药不增加不良反应发生率。
Objective To evaluate the efficacy and safety of Xuesusheng granule combined with sucrose iron in the treatment of patients with iron deficiency anemia after gastric cancer resection. Methods 98 patients with iron deficiency anemia after gastric cancer surgery were randomly divided into the combination group and the monotherapy group. Patients in the 2 groups were treated with iron sucrose after surgery,and Xuesusheng granules were added to the combination group to compare the changes of anemia indicators and adverse drug reactions before and after treatment. Results After treatment,the levels of hemoglobin,hematocrit and serum ferritin in the combined group were higher than those in the single drug group,and the differences were statistically significant. The total effective rate and significant effective rate of the combined group were higher than that of the single drug group,and the differences were statistically significant. After treatment,the scores of TCM symptoms in both groups were reduced compared with those before treatment. During the course of medication,there was no statistically significant difference in adverse reactions between the 2 groups. Conclusion Xuesusheng granule combined with iron sucrose can improve the hemoglobin content,hematocrit,mean red blood cell hemoglobin and serum ferritin level of patients with iron deficiency anemia after gastric cancer surgery,and improve the anemia symptoms,which is more effective than iron sucrose alone,and the combined treatment does not increase the incidence of adverse reactions.
作者
张立晓
ZHANG Lixiao(Hebei People's Hospital,Shijiazhuang,050000)
出处
《实用癌症杂志》
2020年第1期101-103,共3页
The Practical Journal of Cancer
关键词
血速升颗粒
胃癌
贫血
Xuesusheng granule
Gastric cancer
Anemia
