摘要
目的探究知柏地黄丸联合奥硝唑分散片治疗牙周炎的临床效果。方法将该院2018年4月—2019年4月收治的82例牙周炎患者作为调查研究样本,所有患者均给予奥硝唑分散片治疗,然后从中方便抽选出41例患者作为观察组,在奥硝唑分散片治疗基础上联合知柏地黄丸,观察不同用药患者的治疗疗效。结果对照组患者治疗有效率为87.81%,观察组患者治疗有效率为95.12%。且观察组患者治疗后菌斑指数(0.62±0.18)、龈沟出血指数(0.75±0.21)、IL-1(0.83±0.21)ng/mL、TNF-α(3.59±0.87)ng/mL、PGE2(75.65±17.32)ng/mL、VAS评分(1.27±0.32)分、OHIP-14评分(10.22±2.54)分等各项治疗指标均优于对照组患者,差异有统计学意义(t=5.124、5.321、5.228、5.336、5.442、5.155、5.365,P<0.05)。结论知柏地黄丸联合奥硝唑分散片治疗牙周炎临床疗效更为显著,可控制患者牙周病发展,其治疗有效率,进而改善了患者牙周组织状况,为患者的生活质量提升做出保障,有助于抑制患者疾病的快速发展,因此,在临床上,应建议将这种中西医结合治疗方式广泛临床应用推广。
Objective To explore the clinical effect of zhibai dihuang pill combined with Ornidazole Dispersible Tablets in the treatment of periodontitis.Methods A total of 82 patients with periodontitis admitted to the hospital from April 2018 to April 2019 were selected as investigation samples.All patients were treated with Ornidazole Dispersible Tablets,and convenient 41 patients were selected as observation group.On the basis of tinidazole Ornidazole Dispersible Tablets,combined with zhibai dihuang pill,the therapeutic effect of different drugs was observed.Results The effective rate of treatment was 87.81%in the control group,95.12%in the observation group,and the plaque index(0.62±0.18),GCF bleeding index(0.75±0.21),IL-1(0.83±0.21)ng/mL,TNF-α(3.59±0.87)ng/mL,PGE2(75.65±17.32)ng/mL,VAS score(1.27±0.32)points in the observation group.OHIP-14 score(10.22±2.54)points and other therapeutic indexes were better than those in the control group,and there was significant difference between the two groupsthe difference was statistically significant(t=5.124,5.321,5.228,5.336,5.442,5.155,5.365,P<0.05).Conclusion Zhibai Dihuang Pill and Ornidazole Dispersible Tablets in the Treatment of Periodontitis,development can be controlled in patients with periodontal disease and its treatment efficiency,and improve the patients condition of periodontal tissue,to improve the quality of life of patients with security,Help to inhibit the rapid development of disease in patients,therefore,in clinic,should be proposed to this way of combining traditional Chinese and western medicine treatment of wide clinical application promotion.
作者
张凯
ZHANG Kai(Jiangdu Hospital of Traditional Chinese Medicine,Yangzhou,Jiangsu Province,225200 China)
出处
《中外医疗》
2019年第35期175-177,共3页
China & Foreign Medical Treatment
关键词
知柏地黄丸
奥硝唑分散片
牙周炎
临床研究
Zhibai dihuang pill
Ornidazole dispersible tablets
Periodontitis
Clinical research
