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盐酸多奈哌齐辅助治疗血管性痴呆的效果观察 被引量:4

Observation on the effect of donepezil hydrochloride on vascular dementia
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摘要 目的观察盐酸多奈哌齐辅助治疗血管性痴呆的效果。方法采用随机数字表法将本院收治的60例血管性痴呆患者分为实验组(盐酸多奈哌齐组)和对照组(常规组),各30例。比较两组患者治疗前、治疗8周后认知功能[简易精神状态检查(MMSE)、特利尔认知评估量表(MOCA)]评分、血液流变学指标(全血高切还原黏度、全血低切还原黏度、血细胞比容、血浆黏度、纤维蛋白原)变化。结果治疗8周后,两组患者MOCA、MMSE评分均较治疗前升高(P<0.05),实验组高于对照组(P<0.05);两组全血高切还原黏度、全血低切还原黏度、血细胞比容、血浆黏度、纤维蛋白原均低于治疗前,且实验组低于对照组(P<0.05)。结论盐酸多奈哌齐治疗血管性痴呆可改善血流动力学指标,有利于认知功能的恢复。
作者 徐金娥 柳志一 王音 Xu Jin'e;Liu Zhiyi;Wang Yin
出处 《当代医学》 2020年第4期170-171,共2页 Contemporary Medicine
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