摘要
目的探讨影响乙型肝炎肝硬化失代偿期预后的相关因素。方法我院收治的乙型肝炎肝硬化失代偿期患者94例,按预后情况分为存活组和死亡组,分析乙型肝炎肝硬化失代偿期预后的相关危险因素。结果死亡组血清TBiL、TBA水平高于存活组,血清Alb、chol、CHE水平低于存活组,出现腹水、感染、上消化道出血、电解质紊乱、肝性脑病、肝肾综合征并发症、并发症≥3个、脾脏径>4.5 cm、门脉主干内径>1.2 cm、MELD评分≤20分、Child-Pugh评级C级的比例高于存活组(P<0.05);MELD评分、Child-Pugh分级、肝肾综合征、并发症个数≥3个、电解质紊乱是失代偿期肝炎肝硬化独立危险因素。结论MELD评分、Child-Pugh评级、血清TBiL、TBA、Alb、chol、CHE水平与乙型肝炎肝硬化失代偿期预后相关。
Objective To investigate the related factors affecting the prognosis of decompensated hepatitis B cirrhosis.Methods A total of 94 patients with decompensated hepatitis B cirrhosis admitted to our hospital were selected.The patients were divided into survival group and death group according to the prognosis.The related risk factors for prognosis of decompensated hepatitis B cirrhosis were analyzed.Results The levels of serum TBiL and TBA were significantly higher and the levels of serum Alb,chol and CHE were significant lower in the death group than those in the survival group(P<0.05).The incidence rates of complications of ascites,infection,upper gastrointestinal hemorrhage,electrolyte imbalance,hepatic encephalopathy and hepatorenal syndrome in the death group were significantly higher than those in the survival group(P<0.05).The proportion of complication quantity≥3,spleen diameter>4.5 cm,diameter of portal vein>1.2 cm,MELD score≥20 points and Child-Pugh C grade in the death group were significantly more than those in the survival group(P<0.05).MELD score,Child-Pugh grade,hepatorenal syndrome,complication quantity≥3 and electrolyte imbalance were independent risk factors for decompensated hepatitis cirrhosis.Conclusion MELD score,Child-Pugh grade and levels of serum TBiL,TBA,Alb,chol and CHE are correlated with the prognosis of patients with decompensated hepatitis B cirrhosis.
作者
曹敬
梁潇浪
张兰
廖彩兰
CAO Jing;LIANG Xiao-lang;ZHANG Lan;LIAO Cai-lan(Department of Gastroenterology,The Second People's Hospital of Liangshan Yi Autonomous Prefecture,Xichang 615000,China)
出处
《实用医院临床杂志》
2020年第1期171-174,共4页
Practical Journal of Clinical Medicine
关键词
乙型肝炎肝硬化
失代偿期
危险因素
Hepatitis B cirrhosis
Decompensated period
Risk factors
