摘要
目的探讨增液活血汤预防肿瘤患者经外周静脉穿刺中心静脉置管(PICC)置管后静脉血栓形成的效果。方法选取2018年7月~2019年10月我院收治的64例肿瘤PICC置管患者,按照随机数字表法分为观察组(32例)和对照组(32例)。对照组给予预防性护理模式,观察组给予预防性护理模式联合增液活血汤,比较两组的血生化、凝血功能指标的变化情况及静脉血栓的发生情况。结果对照组低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)值高于干预前,高密度脂蛋白胆固醇(HDL-C)值低于干预前,差异有统计学意义(P<0.05);观察组LDL-C值高于干预前,HDL-C值低于干预前,差异有统计学意义(P<0.05);观察组干预前后TG值比较,差异无统计学意义(P>0.05);观察组LDL-C、TG值低于对照组,HDL-C值高于对照组,差异有统计学意义(P<0.05);干预后,对照组D-二聚体(D-D)、纤维蛋白原(FIB)值均高于干预前,活化部分促凝血酶原激酶时间(APTT)、凝血酶原时间(PT)值低于干预前,差异有统计学意义(P<0.05);观察组上述指标与干预前比较,差异无统计学意义(P>0.05);观察组D-D、FIB值低于对照组,APTT、PT值高于对照组,差异有统计学意义(P<0.05);观察组静脉血栓的发生率为9.38%,低于对照组的31.25%,差异有统计学意义(P<0.05)。结论对肿瘤PICC置管患者给予口服增液活血汤联合预防性护理干预模式,有利于改善患者的血生化水平,提高其凝血功能,护理效果显著。
Objective To investigate the effect of Zengyehuoxue Decoction on preventing the formation of venous thrombosis after central vein catheterization via peripheral vein(PICC)in tumor patients.Methods A total of 64 tumor patients with PICC in our hospital from July 2018 to October 2019 were selected and divided into observation group(32 cases)and control group(32 cases)according to random number table method.The control group used preventive nursing mode.The observation group used preventive nursing mode in combination with traditional Chinese medicine Zengyehuoxue Decoction to give patients.The changes of blood biochemical and coagulation indexes and static state,occurrence of vein thrombosis of the two groups were compared.Results The low density lipoprotein chesterol(LDL-C)and triacylglycerol(TG)values of the control group were higher than those before the intervention,and the high density lipoprotein chesterol(HDL-C)values were lower than those before the intervention(P<0.05);the LDL-C values of the observation group were higher than those before the intervention,and the HDL-C values were lower than those before the intervention(P<0.05);the TG values of the observation group before and after the intervention had no statistical significance(P>0.05);the LDL-C and TG values of the observation group were lower than those of the control group,and the HDL-C values were higher than those of the control group,the differences were statistically significant(P<0.05);after intervention,the values of D dimer(D-D)and fibrinogen(FIB)in the control group were higher than those before intervention,and the values of activated partial thromboplastin time(APTT)and prothrombin time(PT)in the observation group were lower than those before intervention,with statistical significance(P<0.05);the values of D-D and FIB in the observation group were lower than those in the control group,and the values of APTT and PT in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05);the incidence of venous thrombosis in the observation group was 9.38%,significantly lower than that in the control group(31.25%),the difference was statistically significant(P<0.05).Conclusion It is beneficial to improve the blood biochemical level,coagulation function and nursing effect of the patients with PICC.
作者
刘怡
LIU Yi(The Third Department of Medicine,Ganzhou Tumor Hospital,Jiangxi Province,Ganzhou341000,China)
出处
《中国当代医药》
2019年第36期226-229,共4页
China Modern Medicine
基金
江西省赣州市科技计划项目（GZ2018ZSF368）
关键词
肿瘤
外周静脉穿刺中心静脉置管
增液活血汤
预防性护理
静脉血栓
Tumor
Central venous catheterization by peripheral venipuncture
Zengyehuoxue Decoction
Preventive nursing
Venous thrombosis
