摘要
目的比较羟考酮与舒芬太尼对宫腔镜手术患者术后恢复质量QoR-40的影响。方法选取2019年3~5月我院择期行宫腔镜手术患者80例。将患者随机分为羟考酮组(O组)和舒芬太尼组(SF组),每组40例。麻醉诱导O组静脉给予羟考酮0.1 mg/kg,SF组静脉给予舒芬太尼0.1μg/kg,两组均丙泊酚维持麻醉。主要观察指标:患者术后24 h QoR-40评分;次要观察指标:术后24 h内不良反应(呼吸抑制,恶心、呕吐,寒战)。结果与SF组比较,O组患者术后24 h QoR-40评分较高[(187.2±3.1)vs.(175.1±5.2),P<0.05],其中,O组患者身体舒适度、情绪状态、心理支持和疼痛感受方面评分较高(P<0.05),而两组自理能力评分差异无统计学意义(P>0.05)。与SF组比较,O组患者术后呼吸抑制,恶心、呕吐,寒战发生率较低(P<0.05)。结论与舒芬太尼0.1μg/kg静脉注射相比,羟考酮0.1 mg/kg静脉注射的宫腔镜手术患者术后24 h QoR-40评分更高,术后呼吸抑制,恶心、呕吐,寒战更少,患者术后恢复质量得到改善。
Objective To compare the effects of oxycodone and sufentanil on postoperative quality of recovery QoR-40 in patients undergoing hysteroscopic surgery.Methods 80 patients who underwent elective hysteroscopy in our hospital from March to May 2019 were selected and randomly divided into the oxycodone group(group O)and the sufentanil group(group SF),with 40 cases in each group.Group O and group SF were given intravenous oxycodone 0.1 mg/kg and intravenous sufentanil 0.1μg/kg respectively for induction of anesthesia.In both groups,propofol was used to maintain anesthesia.The primary observation indicator was the QoR-40 score at 24 hours after surgery.The secondary observation indicator was adverse reaction within 24 hours after surgery,including respiratory depression,nausea,vomiting and chills.Results The QoR-40 score of patients in group O was higher than that in group SF at 24 hours after surgery[(187.2±3.1)vs(175.1±5.2),P<0.05].Among them,scores for physical comfort,emotional state,psychological support and pain perception in group O were higher(P<0.05),but there was no significant difference in self-care ability scores between the two groups(P>0.05).The incidences of respiratory depression,nausea and vomiting,postoperative chills in group O were lower than those in group SF(P<0.05).Conclusion Compared with intravenous sufentanil 0.1μg/kg,intravenous oxycodone 0.1 mg/kg in patients undergoing hysteroscopic surgery shows higher QoR-40 scores at 24 hours after surgery,less postoperative respiratory depression,nausea,vomiting and chills,and improved postoperative quality of recovery.
作者
吴毅欢
周敏
衣欢
WU Yihuan;ZHOU Min;YI Huan(Department of Anesthesiology,Fujian Provincial Maternity and Children's Hospital,Fuzhou 350001,China;Department of Obstetrics and Gynecology,Fujian Provincial Maternity and Children's Hospital,Fuzhou 350001,China)
出处
《中国现代医生》
2019年第36期99-101,共3页
China Modern Doctor
