摘要
为制备一种生物相容性高的医疗级可穿戴电子服装用人体心电(ECG)监测电极,以碳纤维/涤纶复合长丝为电极导电材料,采用刺绣法开发了一种新型刺绣电极,对电极的电学性能和细胞毒性进行分析,并与镀银锦纶/涤纶刺绣电极进行对比;借助自行研发的可穿戴带式心电监测系统评价织物电极采集ECG信号质量。结果表明:镀银电极电学性能较优,但在长期心电信号监测中,碳基电极的阻抗变化与镀银电极相近;对比医用凝胶电极,2种刺绣电极采集到的ECG信号质量良好,均能满足医疗诊断需求;镀银电极具有很强的细胞毒性,其细胞存活率为3%,而碳基电极的细胞存活率为107%,细胞毒性为0级,具有良好生物相容性,符合医疗体外材料测试标准。
Aiming at the preparation of a biocompatible human electrocardiogram(ECG)monitoring electrode for wearable electronic clothing for medical care,a new carbon fiber/polyester embroidery fabric electrode was developed by embroidering carbon fiber/polyester composite filaments to form a conductive material.The electrical properties and cytotoxicity of the electrodes were tested and analyzed.A self-developed wearable belt ECG monitoring system was used to evaluate the quality of the human body ECG signal collected by the carbon fiber/polyester fabric electrodes in comparison with silver-plated polyamide/polyester embroidery electrodes.The results demosntrate that the silver plated electrodes had better electrical properties,but for long-term ECG signal monitoring the impedance of the carbon fiber/polyester electrodes appeared to have similar performance to that of the silver plated electrodes.Compared with the medical gel electrode,the ECG signals collected from the two types of embroidery electrodes demonstrate good quality,meeting the needs for medical diagnosis.Cytotoxicity test revealed that silver-plated electrodes were highly cytotoxic with a cell survival rate of only 3%,whilst for the carbon based electrodes the cell survival rate was 107%with nil cytotoxicity.The research show that the embroidery carbon based electrodes have good biocompatibility and meets the test standard of medical materials in vitro.
作者
董科
李思明
吴官正
黄虹蓉
林钟石
肖学良
DONG Ke;LI Siming;WU Guanzheng;HUANG Hongrong;LIN Zhongshi;XIAO Xueliang(Key Laboratory of Eco-Textiles(Jiangnan University),Ministry of Education,Wuxi,Jiangsu 214122,China;Shenzhen Institute for Drug Control(Shenzhen Testing Center of Medical Devices),Shenzhen,Guangdong 518057,China)
出处
《纺织学报》
EI
CAS
CSCD
北大核心
2020年第1期56-62,68,共8页
Journal of Textile Research
基金
国家重点研发计划项目(2018YFC0810300)
江苏省科技成果转化项目(BA2016117)
福建省新型功能性纺织纤维及材料重点实验室(闽江学院)开放基金项目(FKLTFM1915)
2016江苏省“博士集聚计划”项目(1066010241170090)
关键词
织物电极
碳纤维/涤纶复合长丝
可穿戴监测系统
心电信号
生物相容性
医疗健康
fabric electrode
carbon fiber/polyester composite filament
wearable monitoring system
electrocardiogram signal
biocompatibility
medical health