摘要
目的研究穴位按压联合针对性营养支持对实体瘤患者化疗期间恶心呕吐症状、生活质量及免疫功能的影响。方法选取2018年1月至2019年1月于该院就诊并接受化疗的实体瘤患者100例作为研究对象,按照随机数字表法分为对照组和观察组,每组50例。对照组患者给予常规干预,观察组患者在对照组的基础上进行穴位按压及针对性营养支持。对两组患者化疗后恶心呕吐症状、生活质量及免疫功能进行对比。结果观察组患者在化疗后,不同程度恶心呕吐的发生率明显低于对照组患者,差异有统计学意义(P<0.05)。在化疗后的生活质量评分中,躯体功能、角色功能、社会功能和整体生命质量指标观察组评分结果均优于对照组,差异均有统计学意义(P<0.05)。治疗后观察免疫功能指标,观察组治疗后CD3^+、CD4^+、CD4^+/CD8^+、自然杀伤细胞数量变化优于对照组,差异均有统计学意义(P<0.05)。结论穴位按压联合针对性营养支持可以有效缓解实体瘤患者化疗所导致的恶心呕吐症状,并能在一定程度上提高患者的生活质量及免疫功能。
Objective To study the effect of acupressure combined with targeted nutritional support on nausea and vomiting,quality of life and immune function in patients with solid tumor during chemotherapy.Methods A total of 100 solid tumor patients admitted to the hospital for chemotherapy from January 2018 to January 2019 were selected and randomly divided into the control group and the observation group with 50 patients in each group.Patients in the control group were given routine intervention,and patients in the observation group were given acupressure and targeted nutritional support on the basis of the control group.The nausea and vomiting symptoms,quality of life and immune function of the two groups after chemotherapy were compared.Results After chemotherapy,the incidence of nausea and vomiting in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).In the score of life quality after chemotherapy,the score of body function,role function,social function and overall quality of life the observation group was better than those of the control group,and the differences were statistically significant(P <0.05).After treatment,the changes of CD3^+,CD4^+the percentage of T cell,CD4^+/CD8^+and NK cell in the observation group were significantly better than those in the control group(P<0.05).Conclusion Acupressure combined with targeted nutritional support can effectively alleviate the nausea and vomiting symptoms caused by chemotherapy in patients with solid tumor,and improve the quality of life and immune function of patients to a certain extent.
作者
白涛
李红梅
BAI Tao;LI Hongmei(Department of Integrated Traditional Chinese and Western Medicine,Shaanxi Tumor Hospital,Xi'an,Shaanxi 710061,China)
出处
《检验医学与临床》
CAS
2020年第3期337-340,共4页
Laboratory Medicine and Clinic
关键词
实体瘤
穴位按压
营养支持
恶心呕吐
免疫功能
solid tumor
acupressure
nutritional support
nausea and vomiting
immune function
