摘要
目的:分析医院抗菌药物不良反应(ADRs)发生特点,为促进临床合理使用抗菌药物提供参考。方法:抽取2016年1月-2018年12月间上报的535例抗菌药物ADRs报告,分析其抗菌药物ADRs涉及的相关因素。结果:535例抗菌药物ADRs报告中,其中男性248例,女性287例,女性多于男性;抗菌药物ADRs上报例次逐年增加;静脉给药方式引发的ADRs为最多(占93.46%),其次为口服给药(占6.16%);报告中涉及药品种类中头孢菌素类占26.83%;ADRs报告一般的占93.27%,新的ADRs占4.67%,严重的ADRs占2.06%。结论:医院行政部门应重视抗菌药物不良反应报告和监测工作,合理使用抗菌药物,慎用喹诺酮类药物,以确保患者用药的合理性和安全性。
Objective:To analyze the characteristics of adverse drug reactions(ADR) of antibiotics in a hospital and to promote rational use of antibiotics in clinic. Methods: 535 cases of ADRs reported from January 2016 to December2018 were selected to analyze the related factors involved in ADRs. Results: Among the 535 cases of ADRs, 248 cases were male and 287 cases were female. The number of reported cases of ADRs increased year by year. The most ADRs were induced by intravenous administration(93.46%), followed by oral administration(6.16%).Cephalosporins accounted for 26.83% of the drugs involved in the report.ADRs reported general ADRs(93.27%), new ADRs(4.67%), and severe ADRs(2.06%). Conclusion: The hospital administrative department should attach importance to the reporting and monitoring of adverse reactions of antibacterial drugs, rationally use antibacterial drugs and cautiously use quinolones,so as to ensure the rationality and safety of patients’ medication.
作者
孟祥云
孟汪洋
邢海燕
戴丽
姜怡
李琪
汪星辉
MENG Xiang-yun;MENG Wang-yang;XING Hai-yan;DAI Li;JIANG Yi;WANG Xing-hui(Department of Pharmacy,The No.2 People's Hospital of Hefei,Hefei 230000,China;Medical School of Tongji,Huazhong University of Science and Technology,Huazhong 430030,China)
出处
《抗感染药学》
2019年第11期1930-1934,共5页
Anti-infection Pharmacy
关键词
抗菌药物
不良反应
合理用药
相关因素
antibiotics
adverse drug reactions
rational use of drugs
related factors
