摘要
目的研究化疗肺癌患者实施沙参麦冬汤加减治疗效果。方法选择54例于我院化疗的肺癌患者,时间为2017年2月-2018年3月,根据患者入院时间分为试验组与参照组,每组均27例。参照组采用常规化疗模式,试验组联合沙参麦冬汤加减治疗,对比2组患者治疗前后免疫功能相关指标、药物不良反应情况。结果治疗前2组患者免疫功能相关指标差异无统计学意义(P>0.05),与参照组相比,治疗后试验组CD3^+、CD4^+、CD8^+、CD4^+/CD8^+、NK较高,试验组恶心呕吐、骨髓抑制、肾功能异常、肝功能异常等药物不良反应发生率(18.52%)与参照组(51.85%)相比较低,差异有统计学意义(P<0.05)。结论化疗肺癌患者行沙参麦冬汤加减治疗效果显著。
Objective To study the therapeutic effect of radix astragali radix ophiopogonis decoction plus or minus in chemotherapy for lung cancer patients.Methods 54 patients with lung cancer who received chemotherapy in our hospital from July 2012 to August 2013 were selected.According to the time of admission,the patients were divided into the experimental group and the reference group,with 27 cases in each group.The reference group was treated with conventional chemotherapy,and the experimental group was treated with radix salviae radix ophiopogonis decoction plus or minus treatment,and the immuno-functional indexes and adverse drug reactions of the two groups were compared before and after treatment.Results The two groups before treatment related parameters of immune function in patients with no difference(P>0.05),compared with the control group,experimental group after treatment of CD3^+,CD4^+,CD8^+,CD4^+/CD8^+and NK is higher,the experimental nausea and vomiting,bone marrow suppression,kidney dysfunction,abnormal liver function and the incidence of adverse drug reactions(18.52%)lower than control group(51.85%),show significant differences between groups(P<0.05).Conclusion The curative effect of radix salviae radix ophiopogonis decoction in the treatment of lung cancer patients with chemotherapy is significant.
作者
陈梅
CHEN Mei(Oncology Department,People's Hospital of Wanzhou District,Chongqing 404100,China)
出处
《中国继续医学教育》
2020年第3期143-145,共3页
China Continuing Medical Education
关键词
化疗
肺癌
沙参麦冬汤
免疫功能
加减治疗
不良反应
chemotherapy
lung cancer
Shashen Maidong decoction
immune function
addition and subtraction treatment
adverse reactions