摘要
探讨奥美拉唑联合铝碳酸镁治疗胃溃疡合并胃出血的临床效果。选择2017年10月2018年10月期间苍南县人民医院收治的68例胃溃疡合并胃出血患者,将其随机分为对照组和观察组,每组各34例。两组患者均给予止血处理,并口服果胶铋和抗菌药。对照组采用奥美拉唑治疗,观察组在对照组的基础上增加铝碳酸镁进行治疗,对比两组患者止血、住院和溃疡愈合时间,并观察两组患者的幽门螺杆菌根除效果和不良反应。观察组彻底止血时间(3.03±1.03)d、住院时间(6.03±1.14)d和溃疡愈合时间(24.38±3.36)d均显著低于对照组(5.58±0.96)d、(8.57±1.69)d、(28.39±4.68)d,差异具有统计学意义(P<0.05)。观察组及对照组的不良反应率分别为8.82%、11.76%,对照组不良反应率明显高于观察组,差异具有统计学意义(P>0.05)。疗程结束后的复查结果显示:观察组幽门螺杆菌根除者为27例(79.41%),对照组为21例(61.76%),差异具有统计学意义(P<0.05)。胃溃疡合并胃出血患者常规质子泵抑制剂等药物治疗基础上联用铝碳酸镁片,可缩短患者的康复进程,促进幽门螺杆菌的根除,应用效果良好。
To explore clinical effect of omeprazole combined with aluminum magnesium carbonate in the treatment of gastric ulcer with gastric hemorrhage. From October 2017 to October 2018, 68 patients with gastric ulcer complicated with gastric hemorrhage admitted to Cangnan County People’s Hospital were randomly divided into control group and observation group with 34 cases in each group. Two group patients were given hemostasis treatment, and oral bismuth pectin and antibiotics. The control group was treated with omeprazole, and the observation group was treated with magnesium aluminum carbonate on the basis of the control group. The hemostasis, hospitalization and ulcer healing time of two groups were compared, and the eradication effect and adverse reactions of helicobacter pylori in two groups were observed. The complete hemostasis time (3.03±1.03)d, hospitalization time (6.03±1.14)d and ulcer healing time (24.38±3.36)d in the observation group were significantly lower than those in the control group (5.58±0.96)d, (8.57±1.69)d, (28.39±4.68)d, the difference was statistically significant (P<0.05). The adverse reaction rates of the observation group and the control group were 8.82% and 11.76%, respectively. The adverse reaction rates of the control group were significantly higher than those of the observation group, the difference was statistically significant (P>0.05). The reexamination results after the course of treatment showed that 27 cases (79.41%) in the observation group and 21 cases (61.76%) in the control group were eradicated by helicobacter pylori, the difference was statistically significant (P<0.05). On the basis of conventional proton pump inhibitors and other drugs for patients with gastric ulcer combined with gastric hemorrhage, the combination of aluminum magnesium carbonate tablets can shorten the rehabilitation process of patients, promote the eradication of helicobacter pylori, and the application effect is good.
作者
林荣荣
LIN Rong-rong(Cangnan County People’s Hospital, Cangnan 325800, China)
出处
《黑龙江科学》
2020年第2期88-89,共2页
Heilongjiang Science
关键词
奥美拉唑
铝碳酸镁
胃溃疡
胃出血
幽门螺杆菌
效果观察
Omeprazole
Aluminum carbonate
Gastric ulcer
Gastric hemorrhage
Helicobacter pylori
Effect observation
