摘要
目的:观察妊娠期糖尿病(GDM)产妇剖宫产术前输注钠钾镁钙葡萄糖注射液的应用价值。方法:60例GDM产妇随机分为钠钾镁钙葡萄糖注射液组(实验组)和乳酸钠林格氏液组(对照组),每组30例。入室后按10m l/kg的液体量对产妇进行预负荷,在入室即刻(T0)、预负荷结束麻醉前(T1)、麻醉后5mi n(T2)、断脐带即刻(T3)和术毕即刻(T4),记录产妇平均动脉压(MAP)和心率;在T0、T3、T4抽取产妇动脉血检测血糖和血乳酸水平;记录术中产妇低血压、恶心呕吐及使用血管活性药物的情况。结果:两组产妇各时间点的心率和MAP比较,差异无统计学意义(P>0.05);两组患者术中低血压、恶心呕吐发生率和血管活性药使用率比较,差异无统计学意义(P>0.05);实验组产妇T3、T4的血糖值明显高于对照组,血乳酸水平明显低于对照组(P<0.05)。结论:GDM产妇术前输注钠钾镁钙葡萄糖注射液,有利于维持产妇术中循环稳定,能在安全范围内提高产妇血糖水平,并且不引起乳酸水平的升高。
Objective:To observe the clinical application value of sodium,potassium,magnesium,calcium and glucose injection for pregnant women with gestational diabetes(GDM)before cesarean section.Methods:60 GDM parturients were randomly divided into two groups:sodium,potassium,magnesium,calcium and glucose injection group(experimental group)and lactate Ringer's solution group(control group)with 30 parturients in each group.Preloading was carried out according to 10ml/kg after parturients entering operating room.The mean arterial pressure(MAP)and heart rate of parturients in 2 groups at immediately after entering the operating room(T0),the end of preloading before anaesthesia(T1),5min after anesthesia(T2),immediately after cord cut(T3)and end of operation(T4)were recorded respectivly.The blood glucose and lactate level of parturients were measured by extracting maternal arterial blood at T0,T3,T4.The occurrence of hypotension,nausea and vomiting,as well as using of vasoactive drugs during operation were also recorded.Results:There was no significant difference in heart rate and MAP between the experimental group and control group at each timing(P>0.05).There was no significant difference in incidence rate of hypotension,nausea and vomiting,as well as utilization rate of vasoactive drugs between the two groups(P>0.05).The blood glucose of parturients in experimental group at T3,T4 were obviously higher than control group,but the lactate levels were obviously lower(P<0.05).Conclusions:Using of sodium,potassium,magnesium,calcium and glucose injection for GDM parturients before cesarean section is beneficial to maintain the circulation stability during operation;it also can improve the blood glucose within the safe range,but does not cause increasing of lactate level.
作者
王海生
罗艾静
李艳
WANG Hai-sheng;LUO Ai-jing;LI Yan(Chengde Medical College,Hebei Chengde 067000,China)
出处
《承德医学院学报》
2020年第1期12-15,共4页
Journal of Chengde Medical University
关键词
妊娠期糖尿病(GDM)
钠钾镁钙葡萄糖注射液
剖宫产
Gestational diabetes(GDM)
Sodium
potassium
magnesium
calcium and glucose injection
Cesarean section
