摘要
随着社会的进步和人们生活水平的提高,代谢综合征(MS)的发病率逐年升高,已成为影响人类健康的重要疾病。MS可加快冠心病和其他心脑血管疾病的发生发展,并与胰岛素抵抗、肥胖以及糖代谢、血脂、血压异常密切相关,对人类健康造成严重威胁。高密度脂蛋白(HDL)可逆向转运胆固醇,具有抗炎、抗氧化等功能,对心脑血管具有保护作用。血浆高水平HDL可有效降低MS等多种心脑血管疾病的患病率,对控制 MS以 及相关代谢和心脑血管疾病具有重要意义。
With the progress of society and the improvement of living standards,the incidence of metabolic syndrome(MS) is increasing year by year,and has become an important disease affecting human health.MS can accelerate the occurrence and development of coronary atherosclerotic heart disease and other cardiovascular and cerebrovascular diseases,and is closely related to insulin resistance,obesity,abnormal glucose metabolism,blood lipid and blood pressure,posing a serious threat to human health.High density lipoprotein(HDL) can reverse the transport of cholesterol,which has anti-inflammatory, anti-oxidative and other functions,and has a protective effect on cardiovascular and cerebrovascular.High level of HDL in plasma can effectively reduce the morbidity of MS and other cardiovascular and cerebrovascular diseases,which is of great significance to control MS and related metabolic and cardiovascular and cerebrovascular diseases.
作者
韩菲
殷玲
路国涛
童智慧
丁岩冰
HAN Fei;YIN Ling;LU Guotao;TONG Zhihui;DING Yanbing(School of Medicine,Yangzhou University,Yangzhou 225001,China;Department of Digestive Diseases,the Affiliated Hospital of Yangzhou University,Yangzhou 225001,China;Department of General Surgery Intensive Care Unit,Jinling Hospital,the Affiliated Hospital of Medical College of Nanjing University,Nanjing 210002,China)
出处
《医学综述》
2020年第2期356-360,365,共6页
Medical Recapitulate
基金
国家自然科学基金(81670588,81801970)
关键词
代谢综合征
高密度脂蛋白
胰岛素抵抗
Metabolic syndrome
High density lipoprotein
Insulin resistance
