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甲氨蝶呤联合米非司酮治疗异位妊娠的疗效观察及护理 被引量:4

Efficacy observation and nursing of methotrexate combined with mifepristone in the treatment of ectopic pregnancy
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摘要 目的:探讨甲氨蝶呤联合米非司酮治疗异位妊娠的疗效及护理干预措施。方法:2018年10月-2019年9月收治异位妊娠患者100例,随机分成两组各50例。对照组给予常规护理;观察组给予心理护理干预。比较两组患者阴道止血时间、腹痛消失时间、包块消失时间、血人绒毛膜促性腺激素(β-HCG)转阴时间、包块大小变化及抑郁、焦虑评分。结果:观察组治疗后阴道止血、腹痛消失、包块消失、血β-HCG转阴时间均显著短于对照组,差异有统计学意义(P<0.05)。观察组治疗后包块缩小情况显著优于对照组,差异有统计学意义(P<0.05)。两组护理前抑郁、焦虑评分比较,差异无统计学意义(P>0.05);观察组护理后抑郁、焦虑评分明显低于对照组,差异有统计学意义(P<0.05)。结论:加强心理护理干预、用药后观察和饮食护理干预可明显提高甲氨蝶呤联合米非司酮治疗异位妊娠护理质量和临床疗效。 Objective:To explore the nursing intervention of methotrexate combined with mifepristone in the treatment of ectopic pregnancy,and further improve the quality of nursing.Methods:100 cases of ectopic pregnancy were selected from October 2018 to September 2019,they were randomly divided into the two groups with 50 cases in each group.The control group was given routine nursing and the observation group was given psychological nursing intervention.The time of vaginal hemostasis,the time of abdominal pain disappearance,the time of mass disappearance,the time of bloodβ-HCG turning negative,the change of mass size and the scores of depression and anxiety were compared between the two groups.Results:After treatment,the vaginal hemostasis time,abdominal pain disappearance time,mass loss time,and bloodβ-HCG turning negative time were significantly shorter in the observation group than in the control group,the differences were statistically significant(P<0.05).The reduction of mass in the observation group was significantly better than that in the control group,the difference was statistically significant(P<0.05).There was no significant difference in depression and anxiety scores between the two groups before nursing(P>0.05).The depression and anxiety scores in the observation group after nursing were significantly lower than those in the control group,the difference was statistically significant(P<0.05).Conclusion:Strengthening psychological nursing intervention,post medication observation and diet nursing intervention can significantly improve the nursing quality and clinical effect of methotrexate combined with mifepristone in the treatment of ectopic pregnancy.
作者 陈畅 Chen Chang(General Ward of Beijing First Rehabilitation Hospital(Zhanlan Road Hospital of Xicheng District,Beijing),Beijing 100044)
出处 《中国社区医师》 2020年第3期144-145,共2页 Chinese Community Doctors
关键词 甲氨蝶呤 米非司酮 异位妊娠 疗效 Methotrexate Mifepristone Ectopicpregnancy Curative effect
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