摘要
目的探讨血府逐瘀汤加味在急性心肌梗死保守治疗中的应用效果。方法选取2017年8月~2018年8月我院收治的100例急性心肌梗死患者作为研究对象,按照随机分组法分为对照组(50例)和治疗组(50例)。对照组给予西医常规治疗,治疗组给予中西医结合疗法,在对照组的基础上口服血府逐瘀汤加味,治疗3周,随访6个月。比较两组治疗后的并发症总发生率、两组治疗前后的心功能指标、血压指标、C反应蛋白、白细胞计数、肌红蛋白、天冬氨酸氨基转移酶及脑钠肽水平。结果治疗组的并发症总发生率低于对照组,差异有统计学意义(P<0.05);两组治疗后的心率、舒张压及收缩压比较,差异无统计学意义(P>0.05);治疗组治疗后的左心室射血分数高于对照组,C反应蛋白、白细胞计数、肌红蛋白、天冬氨酸氨基转移酶、脑钠肽水平均低于对照组,差异有统计学意义(P<0.05)。结论接受保守治疗的急性心肌梗死患者应用血府逐瘀汤加味与西药联合治疗,能降低治疗后并发症发生率,改善患者的左心室射血分数和临床相关指标,减轻炎症反应相关指标,值得临床推广应用。
Objective To investigate the application effect of modified Xuefu Zhuyu Decoction in conservative treatment of acute myocardial infarction.Methods A total of 100 patients with acute myocardial infarction admitted to our hospital from August 2017 to August 2018 were selected as the research subjects,they were divided into control group(50 cases)and the treatment group(50 cases)according to the random grouping method.The control group was given conventional western medicine treatment,the treatment group was given traditional Chinese and western medicine therapy,and the Xuefu Zhuyu Decoction was taken orally on the basis of the control group,the treatment was given for 3 weeks and followed up for 6 months.The total incidence of complications after treatment,cardiac function index,blood pressure index,C-reactive protein,white blood cell count,myoglobin,aspartate aminotransferase and brain natriuretic peptide levels before and after treatment were compared between the two groups.Results The total incidence of complications in the treatment group was lower than that in the control group,the difference was statistically significant(P<0.05).There were no significant differences in heart rate,diastolic blood pressure and systolic blood pressure between the two groups after treatment(P>0.05).The left ventricular ejection fraction in the treatment group was higher than that in the control group,and the levels of C-reactive protein,white blood cell count,myoglobin,aspartate aminotransferase,and brain natriuretic peptide were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion The conservative treatment of patients with acute myocardial infarction with Xuefu Zhuyu Decoction combined with western medicine can reduce the incidence of complications after treatment,improve the patients′left ventricular ejection fraction and clinical related indicators,reduce the related indicators of inflammatory response,which is worth clinical promotion and application.
作者
吴秀锋
张新彦
李玉梅
WU Xiu-feng;ZHANG Xin-yan;LI Yu-mei(Department of Traditional Chinese Medicine,Yangchun People′s Hospital of Guangdong Province,Yangchun 529600,China)
出处
《中国当代医药》
2020年第3期152-154,158,共4页
China Modern Medicine
基金
广东省中医药局科研项目（20182177）
关键词
血府逐瘀汤加味
心肌梗死
保守治疗
并发症
心功能
Modified Xuefu Zhuyu Decoction
Myocardial infarction
Conservative treatment
Complications
Cardiac function
