摘要
恶性高热(malignant hyperthermia,MH)是在有易感体质的患者中,由麻醉药或其他因素所诱发而出现的一系列病理生理及临床变化的特定性疾病。该病具有常染色体显性遗传特征,好发于青少年,可伴有唇腭裂等先天性疾病。由于各类麻醉药物在临床医学中的广泛应用,该病越来越受到广大临床医师的重视。MH的治疗手段有其特殊性,误诊和误治可能导致患者死亡等严重后果。制定口腔医学中MH临床诊治中国专家共识的目的,是希望广大口腔临床医师在诊疗过程中警惕MH的发生,减少误诊误治,提高患者的救治成功率。
Malignant hyperthermia(MH) is an autosomal dominant disease induced by anesthetic drugs or other factors and present a series of pathologic physiology and clinical changes in patients with susceptibility. MH is prone to occur in adolescents, and patients may be accompanied by congenital diseases like cleft lip and palate. Due to the wide application of all kinds of anesthetic drugs in clinical procedures, this disease has attracted more and more attention from clinicians.The treatment of MH has its particularity, misdiagnosis and mistreatment may lead to serious consequences even death.The purpose of formulating the consensus of experts on MH in oral medicine is to hope that the majority of oral clinicians are alert to the occurrence of MH in the process of diagnosis and treatment, reduce misdiagnosis and mistreatment of MH,and improve the treatment success rate of patients.
作者
唐瞻贵
步荣发
郭伟
孙沫逸
郑家伟
彭歆
张惠
段小红
姜虹
王淼
张铁军
杨旭东
杨凯
喻建军
罗志勇
谢咏秋
胡延佳
王柏胜
TANG Zhan-gui;BU Rong-fa;GUO Wei;SUN Mo-yi;ZHENG Jia-wei;PENG Xin;ZHANG Hui;DUAN Xiao-hong;JIANG Hong;WANG Miao;ZHANG Tie-jun;YANG Xu-dong;YANG Kai;YU Jian-jun;LUO Zhi-yong;XIE Yong-qiu;HU Yan-jia;WANG Bai-sheng(Department of Oral and Maxillofacial Surgery,Xiangya School of Stomatology,Central South University.Changsha 410013,Hunan Province;Department of Oral and Maxillofacial Surgery,China PLA General Hospital.Beijing 100853;Department of Oromaxillofacial Head and Neck Oncology,Shanghai Ninth People's Hospital,College of Stomatology,Shanghai Jiao Tong University School of Medicine.Shanghai 200011;Department of Oral and Maxillofacial Surgery,School of Stomatology,Airforce Military Medical University.Xi'an 710032,Shaanxi Province;Department of Oral and Maxillofacial Surgery,School of Stomatology,Peking University.Beijing 100081;Department of Anesthesiology,School of Stomatology,Airforce Military Medical University.Xi'an 710032,Shaanxi Province;Oral Biology Section,School of Stomatology,Airforce Military Medical University.Xi'an 710032,Shaanxi Province;Department of Anesthesiology,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine.Shanghai 200011;Department of Anesthesiology,West China School and Hospital of Stomatology,Sichuan University.Chengdu 610041,Sichuan Province;Department of Anesthesiology,School and Hospital of Stomatology,Wuhan University.Wuhan 430070,Hubei Province;Department of Anesthesiology,School of Stomatology,Peking University.Beijing 100081;Department of Oral and Maxillofacial Surgery,The First Affiliated Hospital of Chongqing Medical University.Chongqing 400016;Head and Neck Surgery,Hunan Cancer Hospital.Changsha 410006,Hunan Province;The Centre for Molecular Biodiscovery,School of Life Science,Central South University.Changsha 410083,Hunan Province;Department of Anesthesiology,Xiangya Hospital,Central South University.Changsha 410078,Hunan Province,China)
出处
《中国口腔颌面外科杂志》
CAS
2020年第1期1-9,共9页
China Journal of Oral and Maxillofacial Surgery
基金
国家自然科学基金（81671003）
关键词
口腔医疗
恶性高热
临床诊治
专家共识
Oral medicine
Malignant hyperthermia
Clinical diagnosis and treatment
Expert consensus
