摘要
目的探讨3D打印个性化导板在颅内病变定位和穿刺活组织检查术中的可行性。方法回顾性分析2016年11月至2018年12月于宁夏医科大学总医院神经外科行穿刺活组织检查术的颅内病变患者的临床资料,共8例。以术前头颅CT和MRI增强影像为原始数据,利用Mimics 17.0软件,重建三维图像、规划进针位置、设计穿刺孔道、计算穿刺深度及打印个性化穿刺导板。术中贴合穿刺孔道置入穿刺针,控制穿刺深度,取组织标本送病理学检查。术后以CT结果评估穿刺是否成功。结果术中8例患者的导板与穿刺部位解剖结构贴合好,进针方位、深度均与术前设计方案一致;所有穿刺手术均为1次完成并成功取出目标组织;手术时间为(72.0±10.5)min。术后6 h复查头颅CT,8例患者穿刺通道和穿刺点均未见出血;术后无一例患者发生与手术相关的颅内感染以及新发神经功能缺损症状。结论3D打印个性化导板可简化颅内病变穿刺活组织检查的操作程序,能精准、安全、快速地获取病变组织行病理学检查。
Objective To explore the feasibility of 3D printing individualized guide plate in the localization and biopsy of intracranial lesion.Methods A retrospective analysis was conducted on 8 patients with intracranial lesions who underwent puncture and biopsy at Department of Neurosurgery,General Hospital of Ningxia Medical University from November 2016 to December 2018.Using preoperative brain CT and MRI enhancement images as the original data,Mimics 17.0 software was used to reconstruct the 3D image,plan the needle position,design the puncture hole,and calculate the puncture depth.Personalized puncture guide plate was printed.During the operation,puncture needle was inserted into the fitting puncture hole,the puncture depth was controlled,biopsy specimen was taken for histopathological examination,and postoperative brain CT was used to evaluate the success of puncture.Results During the operation,the guide plates of the 8 patients were well fitted with the anatomical structure of the puncture site,the orientation and depth of the needle entry were consistent with preoperative design scheme,all puncture operations were completed once and the target tissues were successfully removed,and the average operation duration was 72.0±10.5 min.Brain CT was reexamined 6 hours after operation and no bleeding was found in the puncture trajectory and puncture entry points of 8 patients.None of the patients had intracranial infection or new neurological function deficit related to puncture.Conclusion The 3D printed individualized guide plate could simplify the operation procedure of intracranial lesion puncture biopsy and help achieve the purpose of biopsy accurately,safely and efficiently.
作者
吴易洋
王峰
宋子木
刘阳
姬将
陈垚
孙涛
Wu Yiyang;Wang Feng;Song Zimu;Liu Yang;Ji Jiang;Chen Yao;Sun Tao(Ningxia Medical University,Yinchuan 750004,China;Department of Neurosurgery,General Hospital of Ningxia Medical University,Yinchuan 750004,China)
出处
《中华神经外科杂志》
CSCD
北大核心
2020年第1期44-47,共4页
Chinese Journal of Neurosurgery
基金
国家自然科学基金(81660226)
宁夏回族自治区重点研发计划(2018BFG02007)。
