摘要
目的探讨胸腺原发性黏膜相关淋巴组织淋巴瘤(MALToma)的CT表现和诊断价值。方法搜集本院经病理证实的胸腺原发MALToma 7例。观察胸腺MALToma的CT特征,并与6例胸腺癌及6例胸腺弥漫大B细胞淋巴瘤的CT表现进行对照。结果7例MALToma患者中男性2例,女性5例,年龄<40岁者5例(5/7),与胸腺癌(0/6)相比P<0.05),而与弥漫大B细胞淋巴瘤(6/6)比较无统计学差异;胸腺MALToma所有病灶均呈单侧生长(7/7),与弥漫大B细胞淋巴瘤(1/6)比较P<0.05,而与胸腺癌(5/6)比较无统计学意义;所有MALToma病灶均呈囊实性肿块(7/7),囊变区呈小而多发,囊与囊之间分界清楚,囊壁光滑,胸腺癌囊变多呈单个大片坏死(4/6),边缘欠清,弥漫大B细胞淋巴瘤囊变较少见(2/6,P<0.05);所有MALToma病灶均无纵隔淋巴结肿大(0/7),胸腺癌中2例出现淋巴结肿大(2/6),两者比较无统计学差异,而弥漫大B细胞淋巴瘤均有纵隔淋巴结肿大(6/6,P<0.05);所有MALToma病灶均未出现周围大血管侵犯(0/7),与弥漫大B细胞淋巴瘤(5/6)比较P<0.05,而与胸腺癌(2/6)比较无统计学差异。结论CT表现在胸腺原发性MALToma的诊断中具有一定价值。
Objective To investigate the CT manifestations of primary mucosa-associated lymphoid tissue lymphoma(MALToma)of thymus and their diagnostic value.Methods 7 cases of primary thymic MALToma confirmed by pathology were retrospectively collected.The CT features of thymic MALToma were observed and compared with 6 cases of thymic carcinoma and 6 cases of diffuse large B-cell lymphoma.Results Among the 7 MALToma patients,2 were male and 5 were female.5 of 7 were younger than 40 years old,for comparison,the thymic carcinoma was 0/6,where P<0.05,but there was no significant difference in age between MALToma and diffuse large B-cell lymphoma(6/6).Unilateral growth was observed in all MALToma lesions(7/7),in 1 case of the diffuse large B-cell lymphoma(1/6,P<0.05),and in 5 cases of thymic carcinoma(5/6,P>0.05).All MALToma lesions were cystic-solid mass(7/7),with small multiple cysts.The boundary between cysts was clear,and the cystic wall was smooth.The cysts in 4 cases of the thymic carcinoma(4/6)were mostly single necrotic area with unclear margins.The cystic degeneration was observed in 2 cases of diffuse large B-cell lymphoma(2/6,P<0.05).Mediastinal lymph node enlargement was observed in none of the MALToma lesions(0/7),in 2 cases of thymic carcinoma(2/6,P>0.05)and in 6 cases of the diffuse large B-cell lymphoma(6/6,P<0.05);Vascular invasion was observed in none of the MALToma lesions(0/7),in 5 cases of the diffuse large B-cell lymphoma(5/6,P<0.05),and in 2 cases of thymic carcinoma(2/6,P>0.05).Conclusion The CT manifestations are valuable in the diagnosis of primary thymic MALToma.
作者
吴艳玲
张伟
沈杰
俞同福
WU Yanling;ZHANG Wei;SHEN Jie;YU Tongfu(Department of Radiology,The First Affiliated Hospital of Nanjing Medical University,Nanjing 210000,P.R.China)
出处
《医学影像学杂志》
2020年第2期213-216,共4页
Journal of Medical Imaging
