摘要
目的研究原发性慢性肾脏病(Chronic kidney disease,CKD)、肾积水、肾盂扩张3种常见肾脏疾病患儿的预防接种。方法通过北京市顺义区预防接种门诊收集3种常见肾脏疾病患儿诊疗和疫苗接种资料,通过多学科专家论证模式制定预防接种建议并下发接种门诊实施接种,观察接种后不良反应。结果病情稳定的原发性CKD患儿可以安全接种疫苗;接种减毒活疫苗时要考虑所用免疫抑制剂的种类与剂量;患儿B超检查结果为肾积水、肾盂扩张,未用药,临床处置为观察、定期复查的,可正常预防接种。按照接种建议,对3例患儿接种了11种疫苗共20剂次,未发现不良反应。结论本研究形成的预防接种建议为3种常见肾脏疾病患儿及时、安全接种疫苗提供了依据;尚需持续进行接种安全性观察。
Objective To explore vaccination of children with common kidney diseases,including primary chronic kidney disease(CKD),hydronephrosis,and pyelonephrosis.Methods We obtained clinical data and vaccination records of children with any of the above kidney diseases in vaccination clinics of Shunyi district in Beijing and developed vaccination strategy suggestions through multi-disciplinary expert consultation.We vaccinated children with these kidney diseases in immunization clinics as per the suggestions and observed adverse reactions af ter vaccination.Results Children with primary CKD can be safely vaccinated if stable.The type and dosage of immunosuppressive drugs should be considered when administering attenuated live vaccines.Children with B-ultrasonography-confirmed hydronephrosis or pyelonephrosis can be vaccinated normally if no medications are in use that require clinical observation or regular review.Three children with common kidney diseases received 20 doses of 11 different vaccines as per the suggestions,and no adverse reactions were observed.Conclusions Vaccination suggestions f rom this study provide evidence for timely and safe vaccination of children with 3 common kidney diseases.We should continue vaccine safety observations.
作者
肖雷
王凤双
黄蓉
Xiao Lei;Wang Fengshuang;Huang Rong(Shunyi District Center for Disease Control and Prevention,Beijing 101300,China)
出处
《中国疫苗和免疫》
北大核心
2019年第6期705-709,共5页
Chinese Journal of Vaccines and Immunization
基金
2018年首都卫生发展科研专项(首发2018-2-7102)
关键词
慢性肾脏病
肾积水
肾盂扩张
治疗
疫苗接种
Chronic kidney disease
Hydronephrosis
Pyelonephrosis
Treatment
Vaccination
