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扩大改良Morrow术治疗肥厚型梗阻性心肌病的临床分析

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摘要 目的分析扩大改良Morrow术治疗肥厚型梗阻性心肌病(HOCM)的临床价值。方法回顾性分析26例HOCM并行扩大改良Morrow术患者临床资料,分析其术前、术后临床数据,末次随访时症状、心功能分级、心脏彩超检查(室间隔厚度、左室流出道压差、二尖瓣反流)。结果 26里患者中围术期死亡1例,同期行冠脉搭桥3例,同期行二尖瓣置换3例,Ⅲ度房室传导阻滞2例,室间隔穿孔1例。术后超声心动图评估左室流出道压差明显下降(18. 2±11. 5) mm Hg vs.(85. 8±25. 7) mm Hg(P <0. 05);室间隔厚度明显减少(24. 5±5. 6) mm vs.(14. 3±3. 2) mm(P <0. 05);二尖瓣反流明显改善,术后二尖瓣无反流13例、轻度反流8例、中度反流3例、机械瓣术后改变2例,术前二尖瓣无反流3例、轻度反流3例、中度反流8、重度反流12例。1例失访,24例患者完成随访,平均随访3~93(40±27. 2)个月,无远期死亡。主观症状均得到明显改善。随访时心功能均恢复至Ⅰ、Ⅱ级。心脏彩超检查左室流出道压差、室间隔厚度、二尖瓣反流等与术后早期无明显差别。结论扩大改良Morrow术治疗肥厚梗阻性心肌病疗效确切,近中期随访提示能够有效改善症状、提高心功能分级、降低左室流出道压差、减轻二尖瓣反流,有一定的并发症发生率,在可接受范围内。
出处 《临床合理用药杂志》 2019年第35期192-193,共2页 Chinese Journal of Clinical Rational Drug Use
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