摘要
目的了解陕西省第二孩不良出生结局的流行病学现况,探讨第一孩性别对第二孩出生结局的影响。方法利用2010—2013年陕西省出生缺陷现况及其危险因素调查数据,对其中第二孩的不良出生结局进行统计描述,运用Logistic回归分析第一孩性别对第二孩出生结局的影响。结果2010—2013年陕西省第二孩不良出生结局顺位依次为大于胎龄儿(15.88%)、小于胎龄儿(12.27%)、巨大儿(7.16%)、低出生体重儿(4.22%)、早产儿(3.25%)、出生缺陷(2.51%)和过期产儿(2.18%)。巨大儿、大于胎龄儿、低出生体重儿和小于胎龄儿的发生率在性别间的差异有统计学意义(P<0.05)。Logistic回归分析显示,母亲生育第一孩性别为男孩增加了第二孩小于胎龄儿(OR=1.251)发生的可能性,降低了第二孩巨大儿(OR=0.808)和大于胎龄儿(OR=0.873)发生的可能性。结论母亲生育第一孩性别为男孩增加了第二孩小于胎龄儿发生的风险,降低了第二孩巨大儿和大于胎龄儿发生的风险。
Objective To investigate the incidence of the second child's adverse birth outcome in Shaanxi Province and the relationship between sex of the first-born child and the adverse birth outcome of the second-born child.Methods Data used in this study were derived from the prevalence and risk factors of birth defects in Shaanxi Province from 2010 to 2013.Descriptive epidemiological method was used to analyze the data of the second-born child's adverse birth outcome.Logistic regression model was employed to do regression analysis of the factors related to the second-born child's adverse birth outcome.Results Large for gestational age infant and small for gestational age infant accounted for 15.88%and 12.27%,fetal macrosomia and low-birth weight accounted for 7.16%and 4.22%,premature delivery and birth defects accounted for 3.25%and 2.51%,while postmature infant accounted for 2.18%,respectively.Sex differences on large for gestational age infant,small for gestational age infant,fetal macrosomia and low-birth weight existed(P<0.05).Analysis of logistic regression model indicated that for the second-born child,having an elder brother compared with having an elder sister associated with an increased risk of small for gestational age(OR=1.251)and a lower risk of macrosomia(OR=0.808)and large for gestational age(OR=0.873).Conclusion For the second-born child,having an elder brother compared with having an elder sister is associated with an increased risk of small for gestational age and a lower risk of macrosomia and large for gestational age.
作者
吴俊慧
党少农
颜虹
WU Junhui;DANG Shaonong;YAN Hong(Department of Epidemiology and Biostatistics,School of Public Health of Xi'an Jiaotong University Health Science Center,Xi'an 710061,China)
出处
《西安交通大学学报（医学版）》
CAS
CSCD
北大核心
2020年第2期275-280,共6页
Journal of Xi’an Jiaotong University（Medical Sciences）
基金
国家自然科学基金资助项目(No.81230016)
陕西省卫计委出生缺陷防治课题研究(No.SXWSJSWZFCGHT2016-013)~~
关键词
性别
孩次
出生结局
出生体重
流行病学
sex
birth order
birth outcome
birth weight
epidemiology
