摘要
目的:观察妊娠期糖尿病(GDM)患者再次妊娠期间血糖情况,分析复发性GDM的高危因素。方法:选取2016年1月-2018年12月本院住院分娩且前次妊娠诊断为GDM的产妇138例作为研究对象,按照本次妊娠葡萄糖耐量试验(OGTT)结果分为复发性GDM组及血糖正常组,比较两组两次妊娠OGTT值及相关临床指标,分析复发性GDM的高危因素。结果:复发性GDM组本次妊娠与前次妊娠期间空腹血糖(FPG)、1hPG、2hPG值无差异(P>0.05),本次妊娠FPG+1hPG或(和)2hPG异常占比高于前次妊娠(P<0.05),患者年龄≥35岁、孕前体质指数(BMI)≥25kg/m 2、一级亲属糖尿病家族史、前次妊娠1hPG、2hPG值、FPG+1hPG或(和)2hPG异常所占比例均高于血糖正常组(P<0.05);两组间少数民族、有不良孕产史比例、两次妊娠间隔时间、前次妊娠FPG值、前次妊娠血糖控制不良和应用胰岛素的比例无差异(P>0.05)。年龄≥35岁、孕前BMI≥25kg/m 2、前次妊娠2hPG≥9.0mmol/L、FPG+1hPG或(和)2hPG异常是本次妊娠GDM复发的影响因素(P<0.05)。结论:孕妇年龄、孕期BMI及前次妊娠2hPG较高、前次妊娠FPG+1hPG或(和)2hPG异常可能影响再次妊娠复发性GDM,应引起临床注意。
Objective:To observe the blood glucose level of women with history gestational diabetes mellitus(GDM)during pregnancy again,and to analyze the risk factors of recurrent GDM.Methods:138 pregnant women with history GDM were selected as the research objects,and were divided into study group and control group according to the value of glucose tolerance test(OGTT)during pregnancy.The the value of OGTT and clinical index of women were compared between the two groups and between their two-time pregnancy.And the risk factors of recurrent GDM of pregnant women were analyzed.Results:There were no significant different in levels of fasting blood glucose(FPG),1hPG and 2hPG of women between the two-time pregnancy(P>0.05).The proportions of abnormal FPGv+1h PG and abnormal FPG+2hPG during this pregnancy of women with recurrent GDM were significant higher than those of women during previous pregnancy(P<0.05).The rates of women≥35 years old,BMI≥25kg/m 2 before this pregnancy,their first-degree relatives with diabetes,and abnormal FPGv+1h PG and/or abnormal FPG+2h PG during previous pregnancy of women in the study group were significant higher than those of women in the control group(P<0.05).There were no statistically significant different in the proportions of ethnic minorities and adverse pregnancy history,and interval time of two-time pregnancy,FPG value in previous pregnancy,and rates of poor blood glucose controlled and insulin used during previous pregnany of women between the two groups(P>0.05).The women≥35 years old,BMI≥25kg/m 2 before this pregnancy,the level of 2h PG≥9.0mmol/L,and the abnormal FPG+1h PG and/or FPG+2h PG during previous pregnancy were the influencing factors of GDM recurrence(P<0.05).Conclusion:The pregnant women age,BMI before this pregnancy,the level of 2h PG and the abnormal FPG+1h PG and/or FPG+2h PG during previous pregnancy may influence GDM recurrence,so it is should be paid more attention to in clinical practice.
作者
唐晓红
TANG Xiaohong(Pingdingshan Maternal and Child Health Care Hospital,Henan Province,467000)
出处
《中国计划生育学杂志》
2020年第2期247-250,共4页
Chinese Journal of Family Planning
关键词
复发性妊娠期糖尿病
血糖
体质指数
高危因素
Recurrent gestational diabetes mellitus
Blood glucose
Body mass index
Risk factors
