摘要
Background and Originality Content Reduction of esters to corresponding alcohols is a fundamental transformation in organic chemistry.111 Conventionally,this transformation is realized by employing hydride sources or hydrogenation mediated by transition metal catalysts.12,31 The major demerit of metal hydride reduction Is the handling of the intrinsically unsafe pyrophoric and moisture sensitive chemical agents,especially at large scale.Moreover,quenching the excessive reactive metal hydrides during workup and the disposal of the effluent generated may pose additional cumbersome environmental bur-den.pal For transition metal mediated hydrogenation,usually harsh conditions with elevated reaction temperature accompanying with high pressure are mandatory.
基金
We gratefully acknowledge financial support from the National Natural Science Foundation of China(Grant No.21372171)and PAPD.
