摘要
目的探讨生活技能训练对改善慢性精神分裂症病人的认知功能影响。方法选择收治的慢性精神分裂症病人128例,随机将其分为对照组和治疗组,对照组给予常规药物治疗,治疗组在药物治疗的基础上联合生活技能训练,于治疗前和治疗后采用阳性症状和阴性症状(PANSS)量表及事件相关电位P300评定,并进行分析。结果生活技能训练后,治疗组PANSS评定提示阴性、反应缺乏、抑郁因子评分下降(P<0.01或P<0.05);P300靶刺激P3潜伏期缩短,波幅升高(P<0.01),与对照组比较差异均有显著性(P<0.01或P<0.05)。对照组生活技能训练前后P300项目比较差异均无显著性;PANSS抑郁因子评分明显升高(P<0.05),其它因子分比较差异均无显著性。结论生活技能训练对改善慢性精神分裂症患者认知障碍有益。
Objective To investigate the effect of life skills training on cognitive function in patients with chronic schizophrenia.Methods 128 patients with chronic schizophrenia were randomly divided into the control group and the treatment group.The control group was given routine drug therapy.The treatment group combined with life skills training on the basis of drug treatment.Positive symptom and negative symptom(PANSS)scale and event-related potential P300 were used before and after treatment and analyzed.Results after life skills training,PANSS scores in the treatment group were negative,response deficiency and depression factor scores decreased(P<0.01 or P<0.05).The latency of P3 stimulated by P300 target was shortened and the amplitude of P3 was increased(P<0.01),which was significantly different from that of the control group(P<0.01 or P<0.05).In the control group,there was no significant difference in P300 items before and after life skills training,while the scores of PANSS depression factor were significantly higher(P<0.05),and there was no significant difference in other factors between the two groups.Conclusions Life skills training is beneficial to improve cognitive impairment in patients with chronic schizophrenia.
作者
张红军
ZHANG Hongjun(Mental Health Center,Liaoning 110068,China)
出处
《航空航天医学杂志》
2019年第12期1523-1525,共3页
Journal of Aerospace medicine
