摘要
慢性阻塞性肺疾病(COPD)是以持续气流受限为特征的疾病,其与气道、肺组织产生的异常慢性炎症密切相关,中性粒细胞、嗜酸粒细胞、肺泡巨噬细胞、T淋巴细胞等炎性细胞,及脂联素与瘦素、白三烯、肿瘤坏死因子、C-反应蛋白、白细胞介素等炎性介质参与了COPD的发病过程。炎性标志物与COPD的相关研究较多,随着科研技术的进步,未来会有更多炎性标志物被发现,从而为COPD寻找更多新的靶点治疗方向。
inflammatory cells such as neutrophils,eosinophils,alveolar macrophages,and T lymphocytes,and inflammatory mediators such as adiponectin,leptin,leukotrienes,tumor necrosis factor,C-reactive protein and interleukin are involved in the pathogenesis of COPD.There are many studies on inflammatory markers and COPD.With the advance of scientific research techniques,more inflammatory markers will be discovered in the future,which will lead to more new target treatment directions for COPD.
作者
于渌
许光兰
Yu Lu;Xu Guanglan(Guangxi University of Chinese Medicine,Nanning 530000,China;the First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530000,China)
出处
《中国实用医刊》
2019年第24期121-122,F0003,共3页
Chinese Journal of Practical Medicine
关键词
慢性阻塞性肺疾病
T淋巴细胞
脂联素
瘦素
Chronic obstructive pulmonary disease
T lymphocytes
Adiponectin
Leptin
