摘要
目的观察腰硬联合阻滞分娩镇痛对子痫前期孕妇分娩及产后脑钠肽(BNP)、高敏感性肌钙蛋白T(CTnT-hs)的影响。方法选择2017年1月~2018年12月广西壮族自治区南宁市妇幼保健院产科住院待产的120例子痫前期孕妇作为研究对象,按照随机数字表法将其分为观察组及对照组,每组60例。对照组常规解痉、降压处理;观察组在对照组的基础上采用腰硬联合阻滞分娩镇痛。观察组自然分娩孕妇记为观察亚组;对照组自然分娩孕妇记为对照亚组。比较两亚组潜伏期、活跃期、第二产程、分娩后2 h及分娩后第42天BNP、cTnT-hs水平,记录两亚组分娩后第42天血压的发生情况。结果观察组自然分娩45例,对照组自然分娩39例。观察亚组不同产程BNP水平低于对照亚组,差异均有统计学意义(均P<0.05)。两亚组不同产程cTnT-hs比较,差异无统计学意义(P>0.05)。结论腰硬联合阻滞分娩镇痛能降低子痫前期孕妇分娩过程及分娩后BNP水平,降低分娩后第42天高血压的发生率,降低剖宫产率。
Objective To observe the effect of lumbar stiffness combined block for labor analgesia on brain natriuretic peptide(BNP)and high sensitivity troponin T(cTnT-hs)in preeclampsia pregnant women during delivery and postpartum.Methods From January 2017 to December 2018,120 cases with preeclampsia pregnant women who were hospitalized in Department of Anesthesiology,Nanning Maternal and Child Health Hospital,Guangxi Zhuang Autonomous Region were selected as research object.According to the random number table methcd,they were divided into observation group and control group,with 60 cases in each group.Control group was treated with routine spasmolysis,antihypertensive,while observation group was treated with lumbar stiffness combined block for labor analgesia on the basis of control group.Natural childbirth pregnant women of observation group were recorded as the observation subgroup,natural childbirth pregnant women of control group were recorded as the control subgroup.BNP and cTnT-hs levels were compared in the two subgroups during the incubation period,the active period,the second stage of labor,2 h after delivery and the 42nd day after delivery,and the occurrence of blood pressure on the 42nd day after delivery were recorded in the two subgroups.Results There were 45 natural childbirth pregnant women in the observation group and 39 natural childbirth pregnant women in the control group.BNP levels at different stages of labor in the observation subgroup were lower than those in the control subgroup,and the differences were statistically significant(all P<0.05).There were no significant differences in cTnT-hs between the two subgroups at different stages of labor(P>0.05).Conclusion Lumbar stiffness combined block for labor analgesia can reduce the delivery process and post-delivery BNP level of pre-eclampsia pregnant women,reduce the incidence of hypertension on the 42nd day after delivery,and reduce the rate of cesarean section.
作者
劳诚毅
朱茂灵
王宗杰
黄玲
蒋汛
LAO Chengyi;ZHU Maoling;WANG Zongjie;HUANG Ling;JIANG Xun(Department of Anesthesiology,Nanning Maternal and Child Health Hospital,Guangxi Zhuang Autonomous Region,Nanning530011,China)
出处
《中国医药导报》
CAS
2020年第4期127-130,共4页
China Medical Herald
基金
广西南宁市科学研究与技术开发计划（20173017-7）
广西壮族自治区卫生和计划生育委员会自筹经费科研课题（Z20170713）
关键词
子痫前期
分娩镇痛
脑钠肽
高敏感性肌钙蛋白T
产后高血压
Preeclampsia
Labor analgesia
Brain natriuretic peptide
High sensitivity troponin T
Postpartum hypertension
