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老年住院患者血钠水平与衰弱相关性研究 被引量:3

Correlation between serum sodium level and frailty of elderly patients in hospital
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摘要 目的探讨老年住院患者血钠水平与衰弱的相关性。方法选取自2018年1月至2019年3月在北部战区总医院和平院区老年内科住院的患者385例为研究对象,其中,衰弱145例(衰弱组),非衰弱240例(非衰弱组)。收集两组患者的临床一般资料,住院时采血获得相关血常规及肝肾功能、电解质等指标。应用相关回归分析模型分析血钠水平与老年患者衰弱的相关性。结果衰弱组血钠水平为(133.30±3.15)mmol/L,低于非衰弱组的(139.20±3.39) mmol/L,差异有统计学意义(P<0.05)。衰弱组低钠血症发生率为24.1%(35/145),高于非衰弱组的1.7%(4/240),差异有统计学意义(P<0.05)。多元Logistic回归分析结果显示,年龄、白蛋白、低钠血症、血钠水平、共病数为老年人发生衰弱的危险因素。结论老年住院患者入院时的血钠水平低是其发生衰弱的危险因素之一。 Objective To investigate the relationship between frailty and serum sodium concentration in elderly patients in hospital.Methods A retrospective study was performed on 385 cases of patients who were admitted from January 2018 to March 2019,including the frailty group(145 cases of frail)and the non-frailty group(240 cases of frail).The general clinical data of the two groups of patients were collected,and blood samples were collected during hospitalization to obtain relevant blood routine,liver and kidney function,electrolyte and other indicators.The correlation between serum sodium level and frailty in elderly patients was analyzed by correlation regression model.Results The serum sodium level of the frailty group was(133.30±3.15)mmol/L,which was lower than that of the non-frailty group(139.20±3.39)mmol/L,and the difference was statistically significant(P<0.05).The incidence of hyponatremia in the frailty group was 24.1%(35/145),higher than that in the non-frailty group(1.7%,4/240),P<0.05.Multiple Logistic regression analysis showed that age,albumin,hyponatremia,serum sodium level and comorbidity were risk factors for frail in the elderly.Conclusion Low concentration of serum sodium is one of the risk factors of frailty in elderly patients in hospital.
作者 吴炎 边瓯 马宁 张双鹤 胡婉申 WU Yan;BIAN Ou;MA Ning;ZHANG Shuang-he;HU Wan-shen(The Cardre′s Ward,The Heping Branch of General Hospital of Northern Theater Command,Shenyang 110000,China;The First Department of Cardre′s Ward,General Hospital of Northern Theater Command,Shenyang 110016,China)
出处 《临床军医杂志》 CAS 2020年第2期149-151,154,共4页 Clinical Journal of Medical Officers
基金 辽宁省重点研发计划指导项目(2019JH8/10300086)。
关键词 老年 血钠水平 衰弱 Elderly Serum sodium Frail
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