摘要
提出一种新型抗菌材料聚六亚甲基胍盐酸盐(PHMG)接枝的中空纳米二氧化硅(HSN-PHMG)的简便合成方法,PHMG的接枝提高了HSN的水分散性和抗菌性。用扫描电镜(SEM)、透射电镜(TEM)表征纳米二氧化硅的中空结构;傅里叶变换红外光谱(FTIR)、X射线光电子能谱(XPS)和热失重分析(TGA)表征PHMG的成功接枝,HSN-PHMG中PHMG的质量分数约为9.5%;抗菌测试以大肠杆菌(E.coil)和金黄色葡萄球菌(S.aureus)为测试菌种。结果表明:HSN-PHMG对E.coil和S.aureus的最小抑菌浓度(MIC)均为32 mg/L;当HSN-PHMG的浓度为64 mg/L时可以在2 h内完全杀死E.coil。
A simple synthetic method of poly(hexamethylene guanidine hydrochloride) grafted hollow nano-silica(HSN-PHMG), a novel antibacterial material, was proposed. The water dispersibility and antibacterial property of HSN grafting of PHMG were improved. The hollow structure of nano-silica was characterized by scanning electron microscopy(SEM) and transmission electron microscopy(TEM). Fourier transform infrared spectroscopy(FTIR), X-ray photoelectron spectroscopy(XPS) and thermogravimetric analysis were used to characterize the successful grafting of PHMG and the mass fraction of PHMG is about 9.5% in HSN-PHMG. Antibacterial test using Escherichia coil(E.coil) and Staphylococcus aureus(S.aureus) as test strains and the results show that the minimum inhibitory concentration(MIC) of HSN-PHMG on E.coil and S.aureus are all 32 mg/L;E.coil can be completely killed within 2 h when the concentration of HSN-PHMG is 64 mg/L.
作者
张孜文
张康民
杨建军
吴庆云
吴明元
张建安
刘久逸
ZHANG Zi-wen;ZHANG Kang-min;YANG Jian-jun;WU Qing-yun;WU Ming-yuan;ZHANG Jian-an;LIU Jiu-yi(Key Laboratory of Environment-friendly Polymer Materials of Anhui Province,School of Chemistry and Chemical Engineering,Anhui University,Hefei 230601,China)
出处
《材料工程》
EI
CAS
CSCD
北大核心
2020年第3期40-46,共7页
Journal of Materials Engineering
基金
安徽省2017年度科技计划重点项目(1704a0902018)
安徽省高校自然科学研究重点项目(KJ2016A792)
关键词
聚六亚甲基胍盐酸盐
中空纳米二氧化硅
接枝
抗菌
poly(hexamethylene guanidine hydrochloride)
hollow nano-silica
graft
antibacterial
