摘要
目的:利用中医传承辅助平台(TCMISS)探讨崔霞治疗儿童慢性咳嗽的处方用药规律。方法:收集2016年1月至2018年1月崔霞治疗有效的198例慢性咳嗽患儿首诊处方,运用中医传承辅助平台(V2.5)软件建立数据库,采用频次分析、关联规则分析、复杂系统熵聚类等数据挖掘方法,分析处方中各种药物的使用频次、药物之间的关联规律和核心药物组合。结果:共收集198首处方,包含123味中药,其中使用频次较高的药物有辛夷、炙百部、炒白术、桑白皮、炙黄芪、防风、苍耳子、钩藤等,常见药对黄芩-薏苡仁、黄芩-炒白术、防风-薏苡仁、黄芩-姜半夏等,挖掘崔霞治疗儿童慢性咳嗽核心药物组合16条,新处方8首。结论:崔霞治疗小儿慢性咳嗽多从肺脾论治,兼清伏邪,注重温阳化气,消痰散瘀,善于祛风,病证结合。
Objective: To explore the prescription rule of CUI Xia in treating chronic cough in children by using the traditional Chinese medicine supporting platform(TCMISS). Methods: The first-line prescriptions of 198 children with chronic cough who were treated effectively by Cui Xia from January 2016 to January 2018 were collected, and a database was established using the traditional Chinese medicine assistant platform(V2.5)software. Data mining methods such as frequency analysis, association rule analysis, and complex system entropy clustering were used to analyze the frequency of use of various drugs in the prescription, the correlation between drugs, and the core drug combination. Results: A total of 198 prescriptions were collected, including 123 flavors of traditional Chinese medicine. Among the drugs used more frequently are Xinyi(magnolia flower), Baibu(stemona)-fried, Baizhu(white atractylodes)-fried, Sangbaipi(mulberry bark), Huangqi(astragalus)-fried, Fangfeng(saposhnikovia), Cang’erzi(xanthium), Gouteng(uncaria), etc. The common medicine pairs were Huangqin(scutellaria)-Yiyiren(coix), Huangqin(scutellaria)-Baizhu(white atractylodes)-fried, Fangfeng(saposhnikovia)-Yiyiren(coix), Huangqin(scutellaria)-Jiangbanxia(ginger pinellia), etc. We found 16 core drug combinations and 8 new prescriptions of Cui Xia in the treatment of children’s chronic cough. Conclusion: CUI Xia treats children with chronic cough mostly from the lungs and the spleen, and clears away pathogenic factors, pays attention to warming the yang and promoting Qi, eliminating phlegm and removing blood stasis, and is good at removing wind and combining diseases and symptom.
作者
姚楠
郭璠
张宏贤
周倩倩
马宁
闫文宏
崔霞
YAO Nan;GUO Fan;ZHANG Hong-xian;ZHOU Qian-qian;MA Ning;YAN Wen-hong;CUI Xia(Beijing University of Chinese Medicine,Beijing 100029,China;The Third Affiliated Hospital of Beijing University of Chinese Medicine,Beijing 100029,China)
出处
《中医药导报》
2020年第4期90-93,97,共5页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
北京市科技计划课题“首都特色”专项(Z15100004015155)
国家中医药管理局第四批全国中医优秀人才研修项目(国中医药办人教函[2017]124)。
关键词
中医传承辅助平台
崔霞
儿童慢性咳嗽
用药规律
traditional Chinese medicine inheritance support system
CUI Xia
children with chronic cough
medication rules
