摘要
在武汉发生的由新型冠状病毒SARS-CoV-2引发的人类冠状病毒病COVID-19,仅仅2个多月时间在我国及国际上70多个国家出现迅速传播,致病和死亡率高,人类生命受到了极大威胁。一些科学家火速投入研究,对SARS-CoV-2的来源和进化、形态特征和基因结构、感染和致病分子机制开展深入研究,取得了重大进展,为科学防控COVID-19提供了重要依据。根据上述研究的基础,文中对COVID-19病毒疫苗、抗体和抑制剂研发提出了设想,在研究防控COVID-19核心技术上具有一定的参考价值。
The human coronavirus disease COVID-19,caused by the new coronavirus SARS-CoV-2 in Wuhan,China,spread rapidly in China and more than 70 countries globally in just over 2 months.Due to its high morbidity and mortality rate,human beings are under great threat.Some scientists have promptly conducted in-depth researches on the source and evolution of SARS-CoV-2,morphological characteristics and gene structure,molecular mechanisms of infection and pathogenicity.Significant progress has been made,providing an important basis for scientific prevention and control of COVID-19.According to the current research progress,the article puts forward the ideas for the development of COVID-19 virus vaccines,antibodies and inhibitors,which has certain reference value for the study of the core technology in COVID-19 prevention and control.
作者
夏立秋
XIA Liqiu(Hunan Provincial Key Laboratory for Microbial Molecular Biology,State Key Laboratory of Developmental Biology of Freshwater Fish,College of Life Science,Hunan Normal University,Changsha 410081,China)
出处
《激光生物学报》
CAS
2020年第1期1-10,共10页
Acta Laser Biology Sinica
基金
国家自然科学基金项目(31770106)
国家重点基础研究发展计划项目(973计划)(2012CB722301)
湖南省重大研究计划项目(2017NY0103)