摘要
目的探讨去甲肾上腺素对重症脓毒性休克患者肾功能及血流动力学的影响。方法将我院收治的270例重症脓毒性休克患者随机分为对照组和研究组,各135例。对照组给予多巴胺治疗,研究组给予去甲肾上腺素治疗。比较两组患者的治疗效果。结果治疗后24 h,两组患者BUN水平明显降低,CCr水平及每小时尿量均升高,且研究组优于对照组(P<0.05)。治疗后24 h,两组患者MAP和SVRI均升高,CI和HR均降低,且研究组优于对照组(P<0.05)。结论采用去甲肾上腺素治疗重症脓毒性休克患者,可有效改善患者的肾功能和血流动力学。
Objective To investigate the effect of noradrenaline on renal function and hemodynamics in patients with severe septic shock.Methods Two hundred and seventy patients with severe septic shock treated in our hospital were randomly divided into control group and study group,with 135 cases in each group.The control group was treated with dopamine,and the study group was treated with noradrenaline.The treatment effects were compared in both groups.Results At 24 hours after treatment,BUN levels decreased significantly,CCR levels and urine volume per hour increased in the two groups,and those in the study group were better than the control group(P<0.05).At 24 hours after treatment,MAP and SVRI increased in the two groups,CI and HR decreased,and those in the study group were better than the control group(P<0.05).Conclusion Noradrenaline can effectively improve renal function and hemodynamics in patients with severe septic shock.
作者
利军保
LI Jun-bao(Critical Medicine Department,the First People's Hospital of Qinzhou,Qinzhou 535000,China)
出处
《临床医学研究与实践》
2020年第6期57-58,共2页
Clinical Research and Practice
