摘要
目的观察达克罗宁表面麻醉和布托啡诺超前镇痛多途径联合镇痛在胃镜检查时的麻醉效果。方法选取2017年10月~2018年4月于本院行无痛胃镜的患者120例,随机分为A、B、C、D四组,每组30例,四组均静脉缓慢推注丙泊酚进行麻醉诱导,B组在麻醉诱导前10 min含服达克罗宁,C组麻醉诱导前10 min静脉滴注布托啡诺,D组麻醉诱导前10 min静脉滴注布托啡诺的同时含服达克罗宁。比较四组入室时(T0)、进镜时(T1)、术中(T2)、麻醉苏醒即刻(T3)的平均动脉压(MAP)与心率(HR)波动情况,术中丙泊酚追加量、呛咳、体动反应例数、麻醉苏醒时间及不良反应发生情况。结果与A组相比,B、C、D组T0、T1、T2、T3时MAP、HR变化均较平稳,且D组较B、C组平稳,差异有统计学意义(P<0.05);B、C、D组术中丙泊酚追加量、呛咳、体动反应均少于A组,且D组少于B、C组,差异有统计学意义(P<0.05);B、C、D组麻醉苏醒时间、并发症发生率低于A组,且D组低于B、C组,差异有统计学意义(P<0.05)。结论行无痛胃镜时含服达克罗宁联合布托啡诺超前镇痛可有效保证受检者术中生命体征平稳,有助于加快患者苏醒,降低检查时及检查后不良反应,值得临床应用。
Objective To observe the anesthesia effect of multiple analgesia with Dyclonine anesthesia and Butorphanol advanced analgesia during gastroscopy.Methods A total of 120 patients who underwent painless gastroscopy in our hospital from October 2017 to April 2018 were randomly divided into four groups,A,B,C,and D,with 30 patients in each group.The four groups were given intravenous propofol slowly.Phenol was used for induction of anesthesia.Group B contained Dyclonine 10 min before induction of anesthesia.Group C received intravenous infusion of Butorphanol 10 min before induction of anesthesia.Group D anesthesia induced the first 10 min intravenous drip of Butorphanol while taking Dyclonine.Comparison of mean arterial pressure(MAP)and heart rate(HR)fluctuations at room admission(T0),at the time of enteroscopy(T1),during surgery(T2),immediately after anesthesia(T3),and the amount of propofol added during surgery,cough,number of cases of body movements,anesthesia recovery time and occurrence of adverse reactions.Results Compared with group A,the changes of MAP and HR at T0,T1,T2,and T3 were more stable in groups B,C,and D,and group D was more stable than those in groups B and C,the difference was statistically significant(P<0.05);In group B,C,D,the amount of propofol supplementation,cough,and body motion were less than those in group A,and group D was less than those in groups B and C,the differences were statistically significant(P<0.05);The anesthesia wake-up time and the incidence of complications in groups B,C,and D were lower than those in group A,and those in group D were lower than those in groups B and C,the difference was statistically significant(P<0.05).Conclusion The use of Dyclonine combined with Butorphanol advanced analgesia during painless gastroscopy can effectively ensure the stability of vital signs during the operation,help to accelerate patient recovery,reduce adverse reactions during and after examination,and is worth clinical application.
作者
刘槟语
赵金迎
李汝泓
LIU Bin-yu;ZHAO Jin-ying;LI Ru-hong(Department of Anesthesiology,the Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei,China)
出处
《医学信息》
2020年第3期95-98,共4页
Journal of Medical Information
