摘要
目的观察右美托咪定对糖尿病患者行前列腺等离子电切术(TURP)术中血糖的影响。方法选择2018年5月—2019年5月该院收治的60例椎管内麻醉TURP术患者,年龄65~75岁,ASAⅠ~Ⅱ级,随机分为对照组与观察组,各30例。观察组给予负荷剂量0.3μg/kg右美托咪定静脉泵注(15 min),后给予维持剂0.2μg/(kg·h)至手术结束。对照组同样方式给予等容量生理盐水。记录麻醉前(T0)、手术开始(T1)、手术后30 min(T2)、手术结束(T3)时患者静脉血糖的变化。结果观察组患者用药后与对照组相比,观察组患者血糖波动性较小;与观察组相比,对照组血糖值在T2、T3时间点与T0时间点相比持续上升,差异有统计学意义(P<0.05)。结论右美托咪定在糖尿病患者行TURP术中血糖水平更平稳,减少由于血糖变化带来的手术不便。
Objective To observe the effect of dexmedetomidine on blood glucose in patients undergoing prostate plasma resection(TURP).Methods From May 2018 to May 2019,sixty patients with TURP underwent spinal anesthesia in the hospital,aged 65~75 years,ASAI-II,were randomly divided into control group and observation group,30 cases each.The observation group was given a loading dose of 0.3μg/kg dexmedetomidine intravenous injection(15 min),followed by maintenance agent 0.2μg/(kg·h)until the end of the operation.The control group was given an equal volume of normal saline in the same manner.Changes in venous blood glucose were recorded before pre-anesthesia(T0),at the beginning of surgery(T1),30 min after surgery(T2),and at the end of surgery(T3).Results Compared with the control group,the blood glucose level of the observation group was lower in the observation group than in the control group.Compared with the observation group,the blood glucose level of the control group continued to increase at the T2 and T3 time points compared with the T0 time point.The difference was statistically significant(P<0.05).Conclusion Dexmedetomidine is more stable in TURP in diabetic patients,reducing the inconvenience caused by changes in blood glucose.
作者
李丹
康宇
LI Dan;KANG Yu(Department of Anesthesiology,Qiqihar Traditional Chinese Medicine Hospital,Qiqihar,Heilongjiang Province,161000 China)
出处
《糖尿病新世界》
2020年第1期43-44,共2页
Diabetes New World Magazine
