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泪道探通联合药物灌洗治疗慢性泪囊炎的疗效分析

Analysis of lacrimal duct probing and drug lavage in the treatment of chronic dacryocystitis
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摘要 目的分析泪道探通联合药物灌洗治疗慢性泪囊炎的疗效。方法收集自2016年1月~2018年12月期间就诊于我院眼科的慢性泪囊炎患者84例(95眼),随机分为三组:A组(25只眼)生理盐水冲洗泪道,探通后用氯霉素滴眼液冲洗泪道;B组(35只眼)生理盐水冲洗泪道,探通后安尔碘Ⅲ型皮肤黏膜消毒液稀释液冲洗泪道;C组(35只眼)生理盐水冲洗泪道,探通后安尔碘Ⅲ型皮肤黏膜消毒液稀释液冲洗泪道,再将妥布霉素地塞米松眼膏填充在泪囊内。随访至少6个月,计算三组的治愈率、好转率和有效率,并进行荧光染料排泄试验(DDT)。结果 A组有效率为56.00%,B组有效率为68.57%,C组有效率为77.14%,组间两两比较差异有统计学意义(P<0.05)。三组DDT试验阴性患者的荧光素平均排泄时间分别为:A组(4.41±0.52)min,B组(4.01±0.81)min,C组(3.20±0.51)min,各组间差异有统计学意义(P<0.05),证实C组疗效最佳。结论泪道探通联合碘剂灌洗、典必殊眼膏填充泪囊及泪小管的方法操作简单、疗效确切,能有效治疗慢性泪囊炎。 Objective To analyze the efficacy of lacrimal duct probing and drug lavage in the treatment of chronic dacryocystitis. Methods A total of 84 patients(95 eyes) with chronic dacryocystitis who were admitted into the ophthalmology department of our hospital from January 2016 to December 2018 were randomly divided into three groups: group A(25 eyes), the lacrimal duct was rinsed with normal saline, and the lacrimal duct was rinsed with chloramphenicol eye drops after probing;group B(35 eyes), the lacrimal duct was rinsed with normal saline, and the lacrimal duct was rinsed with an iodine type Ⅲ mucous membrane disinfection solution after probing;group C(35 eyes), the lacrimal duct was rinsed with normal saline, and the lacrimal duct was washed with diluent of an iodine type Ⅲ skin and mucous membrane disinfection solution after probing, and then the lacrimal sac was washed with to bramycin dexamethasone eye ointment. They were followed up for at least 6 months. The cure rate, improvement rate and effective rate of the three groups were calculated. And fluorescent dye excretion test(DDT) was conducted. Results The effective rate in group A was 56.00%, and the effective rate in group B was 68.57%, and the effective rate in group C was 77.14%.There was a statistically significant difference among the groups(P<0.05). The average excretion time of fluorescein in three groups of patients with negative DDT test were: group A(4.41±0.52) min, group B(4.01±0.81) min, group C(3.20±0.51) min. The differences between groups were statistical significance(P<0.05), which confirmed that group C had the best effect. Conclusion The method of lacrimal duct probing combined with iodine lavage and Dianbishu eye ointment filling the lacrimal sac and lacrimal canaliculi is simple in operation and effective in treating chronic dacryocystitis.
作者 宋东宇 崔珊珊 夏春光 SONG Dongyu;CUI Shanshan;XIA Chunguang(Department of Ophthalmology,Chaoyang Central Hospital in Liaoning Province,Chaoyang122000,China)
出处 《中国现代医生》 2020年第3期70-74,共5页 China Modern Doctor
关键词 慢性泪囊炎 泪道探通 碘剂灌洗 妥布霉素地塞米松眼膏 Chronic dacryocystitis Lacrimal duct probing Iodine lavage Tobramycin dexamethasone eye ointment
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