摘要
目的:对比分析超声心动图自动心肌运动定量(aCMQ)与三维定量(3DQA)分析技术评测左心室收缩功能的相关性。方法:选取在医院接受超声心动图检查的266例左室收缩功能减低的患者,将左心室射血分数(LVEF)<50%的患者纳入观察组(108例),LVEF≥50%的患者纳入对照组(158例)。收集两组患者左室长轴两腔心观(AP2)、三腔心观(AP3)及四腔心观AP4动态图像;aCMQ测量两腔心纵向应变(AP2LS)、三腔心纵向应变(AP3LS)、四腔心纵向应变(AP4LS)及左心室整体纵向应变(LVGLS);对两组患者左室舒张末期容量(LVEDV)、左室收缩末期容量(LAESV)及LVEF的水平进行计算比较,探讨aCMQ和3DQA两种技术在评估左心室收缩功能方面的相关性。结果:aCMQ技术测量后,观察组LVEF水平明显低于对照组,差异有统计学意义(t=31.059,P<0.01);观察组AP2LS、AP3LS、AP4LS及LVGLS绝对值均明显低于对照组,差异具有统计学意义(t=21.136,t=17.853,t=21.929,t=16.670;P<0.01);对照组中,aCMQ测量的LVEF值与3DQA技术测量的LVEF值呈显著正相关(r=0.73,P<0.01);观察组aCMQ和3DQA技术分别测量的LVEF呈显著正相关(r=0.91,P<0.01);aCMQ测量的LVGLS与3DQA检测的LVEF呈显著负相关(r=-0.815,P<0.05)。重复测量中,同一观察者采用3DQA前后检测LVEF的变异系数为2.81%,不同观察者间的变异系数为3.98%;同一观察者采用aCMQ前后检测LVEF的变异系数为5.28%,不同观察者间的变异系数为4.84%;同一观察者采用aCMQ前后检测LVGLS的变异系数为3.89%,不同观察者间的变异系数为5.97%。结论:aCMQ分析技术可重复性较高,其测量的LVEF值及LVGLS值与3DQA技术检测的结果具有显著相关性,可作为临床评估左心收缩功能的新方法。
Objective:To compare and analyze the correlation of between automated cardiac motion quantitation(aCMQ)by echocardiography and three-dimensional quantitative analysis(3DQA)technique in assessing left ventricular systolic function.Methods:266 patients with reduced left ventricular systolic function who underwent echocardiographic examination were selected.And 108 patients whose left ventricular ejection fractions were less than 50%(LVEF<50%)were divided into observation group,and 158 patients whose those were larger or equal 50%(LVEF≥50%)were divided into control group.The dynamic images of left ventricular long-axis two-chamber view(AP2),three-chamber view(AP3)and four-chamber view(AP3)were collected.Two-chamber longitudinal strain(AP2LS),three-chamber longitudinal strain(AP3LS),four-chamber longitudinal strain(AP4LS)and left ventricle global longitudinal strain(LVGLS)of left ventricular were measured by using aCMQ.Left ventricular end-diastolic volume(LVEDV),left atrial end-systolic volume(LAESV)and LVEF of two groups were calculated and compared.And then,the correlation of aCMQ and 3DQA in assessing left ventricular systolic function was explored.Results:After aCMQ measurement was implemented,the level of LVEF in observation group was significantly lower than that of control group(t=31.059,P<0.01),and the absolute values of AP2LS,AP3LS,AP4LS and LVGLS of observation group were significantly lower than those of control group(t=21.136,t=17.853,t=21.929,t=16.670,P<0.01).In the control group,there was significantly positive correlation between aCMQ and 3DQA techniques for LVEF values(r=0.73,P<0.01).And in observation group,there was significantly positive correlation between aCMQ and 3DQA techniques for LVEF values(r=0.91,P<0.01),while there was significantly negative correlation between the LVGLS values of aCMQ and the LVEF values of 3DQA(r=-0.815,P<0.05).In repeated measures,the coefficient of variation(CV)of detecting LVEF value before and after same observer adopted 3DQA was 2.81%,while that among different observers was 3.98%.And that before and after same observer adopted aCMQ was 5.28%,and that among different observers was 4.84%.And that of detecting LVGLS before and after same observer adopted aCMQ was 3.89%,and that among different observers was 5.97%.Conclusion:The repeatability of aCMQ is higher,and its measured LVEF values and LVGLS values have significantly correlation with the results of 3DQA,and it can be used as a new method of clinical assessment of left ventricular systolic function.
作者
于波
左杰
张成
王国萍
张建平
YU Bo;ZUO Jie;ZHANG Cheng(Department of Physical Diagnosis,Zhongxin Eco-city Hospital,Tianjin Medical University,Tianjin 300467,China)
出处
《中国医学装备》
2020年第3期85-89,共5页
China Medical Equipment
