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甲状腺滤泡癌的术前超声特征与病理亚型的关系 被引量:6

Correlation between preoperative sonographic features and pathological subtypes of follicular thyroid carcinoma
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摘要 目的:探讨甲状腺滤泡癌(Follicular thyroid cancer,FTC)的术前超声特征与病理亚型的相关性。方法:将手术病理证实的35例FTC患者共计35枚病灶的术前超声特征与病理亚型进行相关性分析:根据超声征象分类,FTC分为良性征象滤泡癌组和恶性征象滤泡癌组,比较两组的临床病理及术前超声特征;根据术后病理亚型,FTC分为微小浸润型滤泡癌及广泛浸润型滤泡癌,比较两组的术前超声特征。结果:相比于良性超声征象滤泡癌,恶性超声征象滤泡癌的病理类型更多的是广泛浸润型滤泡癌(P<0.001);形状不规则、边缘不清、有钙化在良恶性超声征象滤泡癌组差异有统计学意义(P=0.045,P<0.001,P=0.015);相比于微小浸润型滤泡癌,广泛浸润型滤泡癌更容易出现边缘不清、不规则周边晕环(P<0.001,P=0.025)。结论:FTC的术前超声特征与病理亚型具有一定的相关性,可根据FTC的超声表现初步预测其病理亚型。 Objective:To investigate the correlation between preoperative sonographic features of follicular thyroid carcinoma(FTC)and its pathological subtypes.Methods:The preoperative sonographic features of 35 lesions in 35 patients and their pathological subtypes were analyzed.Benign FTC were defined as showing none of the accepted ultrasonography criteria for malignancy,and malignant FTC were defined as showing at least one of the accepted ultrasonography criteria for malignancy.Clinicopathologic factors and sonographic features were compared between benign FTC and malignant FTC.Based on the degree of invasiveness from pathology,FTCs were divided into minimally invasive FTC(MI-FTC)and widely invasive FTC(WIFTC).Sonographic features were compared between MI-FTC and WI-FTC.Results:Compared with B-FTC,a significantly higher prevalence of WI-FTC,an irregular shape,an ill-defined margin,and calcification were showed in malignant FTC(P<0.001,P=0.045,P<0.001,P=0.015,respectively).Compared with MI-FTC,an ill-defined margin,and irregular halo ring were more frequent in WI-FTC(P<0.001,P=0.025,respectively).Conclusions:It can be confirmed that there is a significant correlation of preoperative sonographic features of follicular thyroid carcinoma and its pathological subtypes.
作者 林婉玲 丁金旺 包凌云 LIN Wan-ling;DING Jin-wang;BAO Ling-yun(Affiliated Hangzhou First People's Hospital,Zhejiang University School of Medicine,Hangzhou 310006,China)
出处 《中国临床医学影像杂志》 CAS 2020年第2期92-94,共3页 Journal of China Clinic Medical Imaging
关键词 甲状腺肿瘤 超声检查 多普勒 Thyroid neoplasms Ultrasonography,Doppler
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