摘要
目的研究白虎汤加减对老年脑卒中相关性肺炎患者血清降钙素原及淋巴细胞亚群改变的影响。方法选择60例老年脑卒中相关性肺炎患者,分组按照随机数字表法,将60例患者随机均分为两组。两组均给予脑卒中中后预防治疗,对照组给予哌拉西林钠他唑巴坦钠;观察组在此基础上给予白虎汤加减。观察记录两组治疗效果,并检测患者治疗前后PCT、CRP、WBC水平和淋巴细胞亚群的改变。结果在总有效率结果方面,观察组96.67%明显高于对照组80.00%,差异有统计学意义(P<0.05)。治疗后,两组患者PCT、CRP、WBC计数明显降低,观察组显著低于对照组(P<0.05)。两组患者治疗后,观察组CD3^+及CD4^+水平均明显高于对照组,CD4^+/CD8^+明显优于对照组(P<0.05)。结论白虎汤加减能有效改善老年脑卒中相关性肺炎患者血清降钙素原及淋巴细胞亚群水平,疗效确切,值得临床推广应用。
Objective To study the effect of Baihu Decoction on serum procalcitonin and lymphocyte subsets in elderly patients with stroke-associated pneumonia.Methods Sixty elderly patients with stroke-associated pneumonia were randomly divided into two groups according to the random number table method.Both groups were given post-stroke prophylaxis and treatment,while the control group was given piperacillin sodium and tazobactam sodium.The observation group was given Baihu Decoction on this basis.The therapeutic effects of the two groups were observed and recorded and the changes of PCT,CRP,WBC levels and lymphocyte subsets were detected before and after treatment.Results The total clinical effective rate of the observation group was 96.67%,which was significantly higher than that of the control group(80.00%,P<0.05).After treatment,the PCT,CRP and WBC counts of the two groups were significantly decreased while those of the observation group were significantly lower than those of the control group(P<0.05).After treatment,the levels of CD3^+and CD4^+in the observation group were significantly higher than those in the control group,and the levels of CD4^+/CD8^+in the observation group were significantly higher than those in the control group(P<0.05).Conclusion Baihu Decoction can effectively improve the serum procalcitonin and lymphocyte subsets in elderly patients with stroke-related pneumonia.It is effective and worthy of clinical application.
作者
范穗强
孟春想
FAN Suiqiang;MENG Chunxiang(The First Affiliated Hospital of Guangdong Pharmaceutical University,Guangzhou 510515,Guangdong,China;Guangdong Yanling Hospital,Guangzhou 510650,Guangdong,China)
出处
《中华中医药学刊》
CAS
北大核心
2020年第1期245-247,共3页
Chinese Archives of Traditional Chinese Medicine
基金
广东省中医药局科研项目(20142085)。
