摘要
目的观察非急性期脑卒中合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者在应用了持续气道正压通气(CPAP)治疗后,其嗜睡状况及神经系统功能的变化。方法选取本院2017年6月~2019年6月呼吸内科及神经内科住院病例81例非急性期脑卒中合并OSAHS患者,随机分为观察组和对照组,对照组给予卒中非急性期常规治疗,观察组在对照组基础上给予每晚大于6h的CPAP治疗,治疗周期为4周,比较治疗后两组患者嗜睡评分(ESS)、美国国立卫生研究院卒中量表(NIHSS)和日常生活活动能力评定量表(ADL)差异。结果观察组患者嗜睡状况改善,ESS下降,NIHSS降低,ADL升高,疗效结果评估均优于对照组,差异有统计学意义(P<0.05)。结论CPAP治疗在改善非急性期脑卒合并OSAHS患者脑缺氧,促进神经功能恢复方面有较优效果,临床推荐应用。
Objective To observe the changes of sleepiness and neurological function in patients with nonacute stroke complicated with obstructive sleep apnea hypopnea syndrome(OSAHS)after continuous positive airway pressure(CPAP)treatment.Methods 81 patients with non-acute stroke complicated with OSAHS who were hospitalized in the Department of Respiratory Medicine and Department of Neurology of our hospital from June 2017 to June 2019 were selected and randomly divided into observation group and control group.The control group was given conventional treatment for non-acute stroke,and the observation group was given CPAP treatment for more than 6 hours per night on the basis of the control group.The treatment period was 4 weeks.After treatment,the differences of Epworth Sleepiness Scale(ESS),National Institutes of Health Stroke Scale(NIHSS)and Activity of Daily Living Scale(ADL)after treatment were compared between the two groups.Results In the observation group,the patients’sleepiness was improved,ESS and NIHSS were decreased,ADL was increased,and the evaluation of efficacy results was better than the control group.The differences between the two groups were statistically significant(P<0.05).Conclusion CPAP therapy has a superior effect in improving cerebral hypoxia and promoting neurological recovery in patients with non-acute stroke complicated with OSAHS.
作者
徐彦飞
李一禄
陈济明
陶春艳
陈柯颖
王加顿
XU Yanfei;LI Yilu;CHEN Jiming;TAO Chunyan;CHEN Keying;WANG Jiadun(Department of Respiratory and Critical Care Medicine,Xiehe Shenzhen Hospital,Huazhong University of Science and Technology,Guangdong,Shenzhen 518000,China)
出处
《中国医药科学》
2020年第5期19-22,共4页
China Medicine And Pharmacy
